Synthesis kettle for drug reaction
By introducing the crushing box and stirring leaves into the drug reaction synthesis kettle, the problems of real-time observation and drug substance extrusion are solved, and the efficiency and effect of drug reaction are improved.
Patent Information
- Application Number
- CN202420787922.0
- Authority / Receiving Office
- CN · China
- Patent Type
- Utility models(China)
- Current Assignee / Owner
- Filing Date
- 2024-04-16
- Publication Date
- 2024-12-17
- Estimated Expiration
- 2034-04-16
AI Technical Summary
The drug reaction synthesis kettle cannot observe the reaction situation in real time, which affects the effect of drug synthesis and lacks the extrusion structure of solid powdery medicine, resulting in the mixing of agglomerated impurities that affect the reaction.
A synthetic kettle for drug reaction was designed, which includes a crushing box, crushing wheel, stirring leaf and observation window. The crushing wheel and stirring leaf are driven by a motor to crush and mix the medicine, and the reaction is monitored in real time through the observation window.
Effective extrusion treatment of the drug substance is achieved, impurities are mixed, reaction conditions are adjusted in time, and the effect of drug reaction synthesis is improved.
Smart Images

Figure CN222174070U_ABST
Abstract
Description
Technical Field
[0001] The utility model relates to the technical field of drug synthesis, in particular to a synthesis kettle for drug reaction. Background Art
[0002] Reactors are broadly understood as stainless steel containers for physical or chemical reactions. The structural design and parameter configuration of the container are carried out according to different process conditions. The design conditions, process, inspection, manufacturing, and acceptance must be based on relevant technical standards to achieve the heating, evaporation, cooling, and low-speed mixing reaction functions required by the process. Reactors are widely used in petroleum, chemical, rubber, pesticides, dyes, medicines, and foods. They are pressure vessels used to complete processes such as vulcanization, nitration, hydrogenation, hydrocarbonization, polymerization, and condensation, such as reactors, reaction pots, decomposition pots, polymerization pots, etc.
[0003] The current drug reaction synthesis kettle cannot observe the reaction conditions in the synthesis kettle during the reaction synthesis process, and thus cannot make timely adjustments according to the reaction conditions, which affects the reaction synthesis effect of the drug. At the same time, when the solid powdered granular drug material is fed into the reaction kettle, there is a lack of a drug material extrusion structure. When the agglomerated granular impurities are directly mixed into the reaction synthesis kettle, the reaction effect of the drug is affected. In view of the above problems, the inventor proposes a drug reaction synthesis kettle for solving the above problems. Utility Model Content
[0004] In order to solve the problems that the reaction conditions in the synthesis kettle cannot be observed, and thus timely adjustments cannot be made according to the reaction conditions, which affects the reaction synthesis effect of the drug, and the lack of an extrusion structure for the drug materials causes agglomerated granular impurities to be directly mixed into the reaction synthesis kettle, which affects the reaction effect of the drug; the purpose of the utility model is to provide a synthesis kettle for drug reactions.
[0005] In order to solve the above technical problems, the utility model adopts the following technical solutions: a synthesis kettle for drug reaction, including a support, a reaction tank is fixedly connected to the top of the support near the center, a valve two is fixedly connected to the outer ring of the reaction tank near the bottom, a discharge pipe two is fixedly connected to the other end of the valve two, a collecting cup is provided at the top of the support below the discharge pipe two, an observation window is provided at the outer ring of the reaction tank above the valve two, a bracket is fixedly connected to the top of the support near the reaction tank, a crushing box is fixedly connected to the end of the bracket away from the reaction tank near the top center, a crushing wheel is rotatably connected between the inner walls of the crushing box near the center, an auxiliary plate is fixedly connected to the inner wall of the crushing box near the crushing wheel, and the auxiliary plate cooperates with the crushing wheel.
[0006] Preferably, a second motor is fixedly installed near the center of the front end of the pulverizing box, the output end of the second motor passes through the pulverizing box and is fixedly connected to the pulverizing wheel, and a liquid inlet is fixedly connected near the center of the top of the reaction tank.
[0007] Preferably, a feed pipe is fixedly connected at the center of the bottom end of the crushing box, and the other end of the feed pipe passes through the reaction tank. A rotating shaft is rotatably connected at the center of the bottom end of the reaction tank. A plurality of stirring blades are fixedly connected to the outer ring of the rotating shaft near the top, and a spiral stirring blade is fixedly connected to the outer ring of the rotating shaft near the bottom.
[0008] Preferably, a motor 1 is fixedly mounted near the center of the bottom end of the support, and an output end of the motor 1 passes through the support and is fixedly connected to the rotating shaft.
[0009] Preferably, a valve 1 is fixedly connected to the bottom end of the support near the motor, and the top end of the valve 1 passes through the support and is fixedly connected to the reaction tank, and a discharge pipe 1 is fixedly connected to the bottom end of the valve 1.
[0010] Compared with the prior art, the beneficial effects of the utility model are:
[0011] 1. In the utility model, the second motor is operated to rotate the grinding wheel, and then the solid medicine is crushed with the cooperation of the auxiliary plate, thereby solving the problem of lack of an extrusion structure for the medicine, when the agglomerated granular impurities are directly mixed into the reaction and synthesis kettle, affecting the drug reaction effect;
[0012] 2. The utility model solves the problem of being unable to observe the reaction conditions in the synthesis reactor and make timely adjustments, thereby affecting the drug reaction synthesis effect, by running motor 1 and opening valve 2, and then cooperating between stirring blade 1 and spiral stirring blade, observation window and collecting cup. BRIEF DESCRIPTION OF THE DRAWINGS
[0013] In order to more clearly illustrate the embodiments of the utility model or the technical solutions in the prior art, the drawings required for use in the embodiments or the description of the prior art will be briefly introduced below. Obviously, the drawings described below are only some embodiments of the utility model. For ordinary technicians in this field, other drawings can be obtained based on these drawings without paying creative work.
[0014] Figure 1 It is a schematic diagram of the overall structure of the utility model.
[0015] Figure 2 This is a schematic diagram of the cross-sectional structure of the reaction tank of the utility model.
[0016] Figure 3 This is a schematic diagram of the cross-sectional structure of the pulverizing box of the utility model.
[0017] In the figure: 1. Support; 11. Motor 1; 12. Valve 1; 13. Discharge pipe 1; 2. Reaction tank; 21. Liquid inlet; 22. Rotating shaft; 23. Stirring blade 1; 24. Spiral stirring blade; 25. Observation window; 26. Valve 2; 27. Discharge pipe 2; 28. Collecting cup; 3. Bracket; 31. Crushing box; 32. Crushing wheel; 33. Discharge pipe; 34. Auxiliary plate; 35. Motor 2. DETAILED DESCRIPTION
[0018] The following will be combined with the drawings in the embodiments of the utility model to clearly and completely describe the technical solutions in the embodiments of the utility model. Obviously, the described embodiments are only part of the embodiments of the utility model, not all of the embodiments. Based on the embodiments in the utility model, all other embodiments obtained by ordinary technicians in this field without creative work are within the scope of protection of the utility model.
[0019] Example: Figure 1-3 As shown, the utility model provides a technical solution: a synthesis reactor for drug reaction, including a support 1, a reaction tank 2 is fixedly connected to the top of the support 1 near the center, a valve 2 is fixedly connected to the outer ring of the reaction tank 2 near the bottom, and a discharge pipe 2 27 is fixedly connected to the other end of the valve 26, a collecting cup 28 is provided at the top of the support 1 below the discharge pipe 27, an observation window 25 is provided at the outer ring of the reaction tank 2 above the valve 26, and the observation window 25 is made of transparent glass, a bracket 3 is fixedly connected to the top of the support 1 near the reaction tank 2, a crushing box 31 is fixedly connected to one end of the bracket 3 away from the reaction tank 2 near the top center, a crushing wheel 32 is rotatably connected between the inner walls of the crushing box 31 near the center, an auxiliary plate 34 is fixedly connected to the inner wall of the crushing box 31 near the crushing wheel 32, and the auxiliary plate 34 cooperates with the crushing wheel 32.
[0020] A second motor 35 is fixedly installed near the center of the front end of the crushing box 31 , and the output end of the second motor 35 passes through the crushing box 31 and is fixedly connected to the crushing wheel 32 .
[0021] By adopting the above technical solution, the second motor 35 is operated, so that the fixedly connected grinding wheel 32 is rotated, and the outer ring of the grinding wheel 32 is provided with a protrusion, so as to facilitate the crushing of the granular medicine.
[0022] A liquid inlet 21 is fixedly connected to the top of the reaction tank 2 near the center.
[0023] By adopting the above technical solution, a liquid inlet 21 is provided at the top of the reaction tank 2 in order to facilitate the addition of liquid medicine into the reaction tank 2 .
[0024] A feeding pipe 33 is fixedly connected to the center of the bottom end of the crushing box 31 , and the other end of the feeding pipe 33 passes through the reaction tank 2 .
[0025] By adopting the above technical solution, an inclined discharge pipe 33 is provided at the bottom end of the crushing box 31 to facilitate the delivery of the crushed medicine to the reaction tank 2 .
[0026] A rotating shaft 22 is rotatably connected at the center of the bottom end of the reaction tank 2. A plurality of stirring blades 23 are fixedly connected to the outer ring of the rotating shaft 22 near the top. A spiral stirring blade 24 is fixedly connected to the outer ring of the rotating shaft 22 near the bottom.
[0027] By adopting the above technical solution, the rotating shaft 22 rotates, thereby causing the fixedly connected stirring blade 23 and the spiral stirring blade 24 to rotate.
[0028] A motor 11 is fixedly installed near the center of the bottom end of the support 1, and the output end of the motor 11 passes through the support 1 and is fixedly connected to the rotating shaft 22.
[0029] By adopting the above technical solution, the motor 11 is operated so that the fixedly connected rotating shaft 22 rotates.
[0030] A valve 12 is fixedly connected to the bottom end of the support 1 near the motor 11, and the top end of the valve 12 penetrates the support 1 and is fixedly connected to the reaction tank 2.
[0031] By adopting the above technical solution, valve 12 is opened, so that the drug solution in the reaction tank 2 can be discharged.
[0032] The bottom end of the valve 12 is fixedly connected with a discharge pipe 13.
[0033] By adopting the above technical solution, a discharge pipe 13 is set at the bottom end of the valve 12 to cooperate with the valve 12 to discharge the drug solution.
[0034] Working principle: When the device is used, the liquid medicine is firstly added into the reaction tank 2 through the liquid inlet 21, and then the solid medicine is added into the crushing box 31 and the motor 2 35 is operated, so that the fixedly connected crushing wheel 32 is rotated, and then the solid medicine is crushed with the cooperation of the auxiliary plate 34, and finally the solid medicine is transported into the reaction tank 2 through the feeding pipe 33, so as to achieve the effect of crushing the solid medicine, thereby solving the problem that the agglomerated granular impurities are directly mixed into the reaction synthesis kettle due to the lack of an extrusion structure for the medicine, which affects the drug reaction effect;
[0035] After the solid medicine and the liquid medicine are simultaneously delivered to the reaction tank 2, the motor 11 can be operated so that the fixedly connected rotating shaft 22 drives the stirring blade 23 and the spiral stirring blade 24 to rotate, so as to realize the reaction and mixing of the medicines. The reaction inside the reaction tank 2 can be observed through the observation window 25, and then the valve 26 is opened to deliver the reacting medicine to the collecting cup 28. At this time, the drug solution in the collecting cup 28 can be observed, thereby solving the problem that the reaction situation in the synthesis reactor cannot be observed and adjusted in time, which affects the drug reaction synthesis effect.
[0036] Obviously, those skilled in the art can make various changes and modifications to the present invention without departing from the spirit and scope of the present invention. Thus, if these modifications and variations of the present invention fall within the scope of the claims of the present invention and their equivalents, the present invention is also intended to include these modifications and variations.
Claims
1. A synthesis reactor for drug reaction, comprising a support (1), characterized in that: A reaction tank (2) is fixedly connected to the top of the support (1) near the center, a valve 2 (26) is fixedly connected to the outer ring of the reaction tank (2) near the bottom, and a discharge pipe 2 (27) is fixedly connected to the other end of the valve 2 (26). A collecting cup (28) is provided at the top of the support (1) below the discharge pipe 2 (27), and an observation window (25) is provided at the outer ring of the reaction tank (2) above the valve 2 (26). A bracket (3) is fixedly connected to the top of the support (1) near the reaction tank (2), and a crushing box (31) is fixedly connected to one end of the bracket (3) away from the reaction tank (2) near the top center. A crushing wheel (32) is rotatably connected between the inner walls of the crushing box (31) near the center, and an auxiliary plate (34) is fixedly connected to the inner wall of the crushing box (31) near the crushing wheel (32), and the auxiliary plate (34) cooperates with the crushing wheel (32).
2. A synthesis reactor for drug reaction as claimed in claim 1, characterized in that: A second motor (35) is fixedly mounted near the center of the front end of the pulverizing box (31), and an output end of the second motor (35) passes through the pulverizing box (31) and is fixedly connected to the pulverizing wheel (32).
3. A synthesis reactor for drug reaction as claimed in claim 1, characterized in that: A liquid inlet (21) is fixedly connected to the top of the reaction tank (2) near the center.
4. A synthesis reactor for drug reaction as claimed in claim 1, characterized in that: A feeding pipe (33) is fixedly connected to the center of the bottom end of the pulverizing box (31), and the other end of the feeding pipe (33) passes through the reaction tank (2).
5. A synthesis reactor for drug reaction as claimed in claim 1, characterized in that: A rotating shaft (22) is rotatably connected at the center of the bottom end of the reaction tank (2), a plurality of stirring blades (23) are fixedly connected to the outer ring of the rotating shaft (22) near the top, and a spiral stirring blade (24) is fixedly connected to the outer ring of the rotating shaft (22) near the bottom.
6. A synthesis reactor for drug reaction as claimed in claim 5, characterized in that: A motor 1 (11) is fixedly mounted near the center of the bottom end of the support (1), and the output end of the motor 1 (11) passes through the support (1) and is fixedly connected to the rotating shaft (22).
7. A synthesis reactor for drug reaction as claimed in claim 6, characterized in that: A valve (12) is fixedly connected to the bottom end of the support (1) near the motor (11), and the top end of the valve (12) penetrates the support (1) and is fixedly connected to the reaction tank (2).
8. A synthesis reactor for drug reaction as claimed in claim 7, characterized in that: The bottom end of the valve 1 (12) is fixedly connected to a discharge pipe 1 (13).
