Efficient mixing granulator for pharmacy

Abstract

The utility model discloses an efficient mixing granulator for pharmacy, which comprises a mixing bin, the top of the mixing bin is provided with a feeding port, and the bottom of the inner cavity of the mixing bin is fixedly provided with a fixed cylinder. After a rotating shaft drives a stirring plate to stir and mix raw materials, an extrusion assembly in a fixed barrel drives the raw materials to be extruded out of a discharging hole in the bottom of the fixed barrel, meanwhile, the raw materials fall onto the mold plate, and in the transferring process, the mold plate is matched with an adjusting assembly, and the mold plate is mutually closed; by means of the method, it can be guaranteed that the sizes of the pills are uniform, meanwhile, before the raw materials are injected into the mold plates, the mold plates are conveniently smeared with a release agent, the pills can be conveniently demolded from the mold plates, meanwhile, the pills are not prone to adhering to one another, and the pills are kept independent after falling down; and the pill processing is improved.

Description

Technical Field

[0001] This utility model relates to the field of drug granulation technology, specifically to a high-efficiency mixing granulator for pharmaceutical use. Background Technology

[0002] A pellet mill mainly consists of a feeding, mixing, pelleting, transmission, and lubrication system, and is widely used in the pharmaceutical, chemical, and food industries. Pellet mills can be divided into feed pellet mills and biomass energy pellet mills.

[0003] In the prior art, Chinese utility model publication number CN218047786U discloses a high-efficiency pharmaceutical wet granulation machine, specifically relating to the field of wet pharmaceutical equipment technology. Currently, most wet granulation processes involve separate mixing and granulation, which not only results in low pharmaceutical efficiency but also increases the risk of raw material contamination. The proposed machine includes a housing, a mixing shaft with a stirring rod arranged in a circular array fixed at the end away from the first motor, and a symmetrically distributed first rotating shaft rotatably inserted inside the housing. A tilting plate is fixedly fitted onto the outer side of the first rotating shaft. The end of the output shaft of the first motor drives the mixing shaft to rotate, which in turn drives the stirring rods to rotate, mixing the raw materials. The first rotating shaft then drives the tilting plate to rotate, causing the mixed raw materials to fall into the circular plate. Finally, the end of the output shaft of a third motor drives a cutting blade to rotate, cutting the raw materials in the forming holes. This avoids the low efficiency caused by separate processing, thus achieving rapid pharmaceutical manufacturing.

[0004] In the above technical solution, the raw material is scraped into the forming hole by a scraper, and granular pills are formed in the forming hole. However, the shape and size of the pills formed by extrusion through the forming hole cannot be guaranteed. In addition, how can the formed pills be separated from the forming hole? Because the drug has a certain viscosity during the stirring process, the integrity of the pill formation must be guaranteed. Here, the pills are formed and adhered in the forming hole, making it difficult for them to fall. Even if they fall, they will stick together in the sieve plate, making them difficult to separate and affecting the granulation efficiency of the drug. Utility Model Content

[0005] The purpose of this invention is to provide a high-efficiency mixing and granulation machine for pharmaceuticals. A rotating shaft drives a mixing plate to mix raw materials. The extrusion assembly then conveys the mixed materials downwards from a fixed cylinder. The materials are then extruded from the discharge port into a lower mold plate. As the rotating shaft rotates, the mold plate moves to the bottom of the mixing chamber. Subsequently, the two sets of mold plates close together with the assistance of an adjusting assembly, forming a complete pill from the materials on both mold plates. This not only ensures the pill size but also allows for the application of a release agent to the mold plate before the drug enters, preventing the pills from sticking together and facilitating demolding. This improves granulation efficiency and solves the problems mentioned in the background art.

[0006] To achieve the above objectives, this utility model provides the following technical solution: a high-efficiency mixing granulator for pharmaceuticals, comprising a mixing hopper, a feeding port at the top of the mixing hopper, a fixed cylinder fixed at the bottom of the inner cavity of the mixing hopper, the bottom of the fixed cylinder penetrating the mixing hopper and extending downward, an extrusion assembly for conveying drugs downwards being provided inside the fixed cylinder, multiple sets of discharge holes being provided at the bottom of the fixed cylinder, a rotating shaft being rotatably connected to the center of the inner cavity of the mixing hopper via a bearing, the bottom of the rotating shaft penetrating to the bottom of the mixing hopper and fixed with multiple sets of connecting rods, a fixed frame being fixed at the end of the connecting rods away from the rotating shaft, two sets of movable shafts being rotatably connected to the inner cavity of the fixed frame via a bearing, a mold plate being fixed to the outer side of the movable shaft, and an adjustment assembly for closing the mold plate being provided at the bottom of the mixing hopper.

[0007] Preferably, the adjusting assembly includes two sets of chambers opened inside the fixed frame. One end of the movable shaft passes through one set of chambers and is fixed with an adjusting gear. The opposing sides of the adjusting gear are meshed with intermeshing transition gears. The transition gears rotate within the chambers. The other end of the movable shaft passes through the outside of the fixed frame and is fixed with a rotating gear. A connecting frame is fixed at the bottom of the mixing bin. An arc-shaped rack plate that meshes with the rotating gear is fixed on the inner side of the connecting frame.

[0008] Preferably, the extrusion assembly includes a first motor fixed to the top of the fixed cylinder, the output shaft of the first motor passing through the fixed cylinder and having a stirring shaft fixed thereon, a spiral blade fixed to the outside of the stirring shaft, and the top of the mold plate fitting against the bottom of the fixed cylinder.

[0009] Preferably, a torsion spring is fixed to the outside of the movable shaft, and the end of the torsion spring away from the movable shaft is fixed to the fixed frame.

[0010] Preferably, a second motor is fixed to the top of the mixing hopper, the output shaft of the second motor passes through the inner cavity of the mixing hopper and is fixedly connected to one end of the rotating shaft, and a stirring plate is fixed to the outside of the rotating shaft.

[0011] Preferably, the bottom of the mixing hopper is provided with a powder brushing structure for applying release agent to the mold plate.

[0012] Preferably, a collection funnel is fixed to the bottom of the mixing hopper, and support feet are fixed around the bottom of the mixing hopper on the outside of the collection funnel.

[0013] Compared with the prior art, the beneficial effects of this utility model are:

[0014] This invention uses a rotating shaft to drive a connecting rod to rotate multiple sets of fixed frames. These fixed frames then cause the mold plates to rotate periodically at the bottom of the mixing chamber. After the rotating shaft drives the stirring plate to mix the raw materials, the extrusion assembly inside the fixed cylinder pushes the raw materials out of the discharge hole at the bottom of the fixed cylinder. Simultaneously, the raw materials fall onto the mold plates. During the transfer process, the mold plates, with the assistance of the adjusting assembly, close together, combining the raw materials from the two sets of mold plates into a complete pill. This method not only ensures uniform pill size but also facilitates the application of a release agent to the mold plates before the raw materials are injected. This makes it easy for the pills to be demolded from the mold plates, and also prevents the pills from sticking together, keeping them independent after falling, thus improving pill processing.

[0015] This invention uses a torsion spring to conveniently limit the movement of the movable shaft, keeping the two sets of mold plates in a horizontal state, so that the mold plates fit snugly against the bottom of the fixed cylinder, facilitating the injection of raw materials into the mold plates. Attached Figure Description

[0016] Figure 1 This is a three-dimensional structural diagram of the present invention;

[0017] Figure 2 This is a cross-sectional perspective view of the mixing hopper and collecting funnel of this utility model.

[0018] Figure 3 This is a partial bottom-view three-dimensional structural diagram of the present invention;

[0019] Figure 4 This is a three-dimensional structural diagram of the fixing frame and mold plate of this utility model;

[0020] Figure 5 This is a top view cross-sectional three-dimensional structural diagram of the fixing frame of this utility model;

[0021] Figure 6 This is a cross-sectional three-dimensional structural diagram of the fixing cylinder of this utility model.

[0022] The following are the labeling elements in the diagram: 1. Mixing bin; 2. Fixed cylinder; 3. Extrusion assembly; 31. First motor; 32. Stirring shaft; 33. Spiral blade; 4. Discharge hole; 5. Rotating shaft; 6. Fixed frame; 7. Movable shaft; 8. Mold plate; 9. Adjustment assembly; 91. Adjusting gear; 92. Transition gear; 93. Rotating gear; 94. Connecting frame; 95. Arc-shaped rack plate; 10. Torsion spring; 11. Second motor; 12. Stirring plate; 13. Powder brushing structure; 14. Collection funnel. Detailed Implementation

[0023] The technical solutions of the present utility model will be clearly and completely described below with reference to the accompanying drawings of the embodiments. Obviously, the described embodiments are only some embodiments of the present utility model, and not all embodiments. Based on the embodiments of the present utility model, all other embodiments obtained by those of ordinary skill in the art without creative effort are within the protection scope of the present utility model.

[0024] This utility model provides, for example Figures 1-6 The pharmaceutical high-efficiency mixing granulator shown includes a mixing bin 1, a feeding port at the top of the mixing bin 1, a fixed cylinder 2 fixed at the bottom of the inner cavity of the mixing bin 1, the bottom of the fixed cylinder 2 penetrating the mixing bin 1 and extending downward, an extrusion assembly 3 for conveying drugs downward is provided inside the fixed cylinder 2, multiple sets of discharge holes 4 are provided at the bottom of the fixed cylinder 2, a rotating shaft 5 is rotatably connected to the center of the inner cavity of the mixing bin 1 via a bearing, the bottom of the rotating shaft 5 penetrates to the bottom of the mixing bin 1 and is fixed with multiple sets of connecting rods, a fixed frame 6 is fixed at the end of the connecting rod away from the rotating shaft 5, two sets of movable shafts 7 are rotatably connected to the inner cavity of the fixed frame 6 via a bearing, a mold plate 8 is fixed to the outside of the movable shaft 7, and an adjustment assembly 9 for closing the mold plate 8 is provided at the bottom of the mixing bin 1.

[0025] The rotating shaft 5 drives the connecting rod to rotate multiple sets of fixed frames 6, causing the fixed frames 6 to drive the mold plate 8 to rotate periodically at the bottom of the mixing chamber 1. After the rotating shaft 5 drives the stirring plate 12 to stir and mix the raw materials, the extrusion component 3 in the fixed cylinder 2 drives the raw materials to be extruded from the discharge hole 4 at the bottom of the fixed cylinder 2. At the same time, the raw materials fall onto the mold plate 8. During the transfer process, the mold plate 8 is coordinated by the adjusting component 9, and the mold plates 8 close together to combine the raw materials on the two sets of mold plates 8 into a complete pill. This method can not only ensure the uniformity of pill size, but also facilitate the application of release agent to the mold plate 8 before the raw materials are injected into the mold plate 8. This not only makes it easy for the pills to be demolded from the mold plate 8, but also prevents the pills from sticking together and keeps them independent after falling, thus improving the pill processing.

[0026] Among them, such as Figure 2-5 As shown:

[0027] The adjusting assembly 9 includes two sets of chambers inside the fixed frame 6. One end of the movable shaft 7 passes through one set of chambers and is fixed with an adjusting gear 91. The opposing side of the adjusting gear 91 is meshed with a transition gear 92, which rotates within the chamber. The other end of the movable shaft 7 passes through the outside of the fixed frame 6 and is fixed with a rotating gear 93. A connecting frame 94 is fixed at the bottom of the mixing chamber 1. An arc-shaped rack plate 95 that meshes with the rotating gear 93 is fixed on the inner side of the connecting frame 94. Through the cooperation of the adjusting gear 91 and the transition gear 92, the two sets of movable shafts 7 can be linked together. Then, after the rotating gear 93 on one set of movable shafts 7 meshes with the arc-shaped rack plate 95, it drives the mold plates 8 to close together and complete the mold closing.

[0028] Furthermore, such as Figure 6 As shown:

[0029] The extrusion assembly 3 includes a first motor 31 fixed to the top of the fixed cylinder 2. The output shaft of the first motor 31 passes through the fixed cylinder 2 and is fixed with a stirring shaft 32. A spiral blade 33 is fixed to the outside of the stirring shaft 32. The top of the mold plate 8 is attached to the bottom of the fixed cylinder 2. The stirring shaft 32 is driven to rotate by the first motor 31, which drives the spiral blade 33. The raw material in the initial mixing chamber 1 is extruded and conveyed downward from the fixed cylinder 2.

[0030] Preferred, such as Figure 5 As shown:

[0031] A torsion spring 10 is fixed to the outside of the movable shaft 7. The end of the torsion spring 10 away from the movable shaft 7 is fixed to the fixed frame 6. With the cooperation of the torsion spring 10, the movable shaft 7 can be limited so that the two sets of mold plates 8 are kept in a horizontal state, so that the mold plate 8 is in contact with the bottom of the fixed cylinder 2, which facilitates the injection of raw materials into the mold plate 8.

[0032] It is worth noting that, such as Figure 2 As shown:

[0033] A second motor 11 is fixed to the top of the mixing hopper 1. The output shaft of the second motor 11 passes through the inner cavity of the mixing hopper 1 and is fixedly connected to one end of the rotating shaft 5. A stirring plate 12 is fixed to the outside of the rotating shaft 5. The second motor 11 drives the rotating shaft 5 to rotate, and the stirring plate 12 mixes the raw materials in the mixing hopper 1.

[0034] In a further preferred embodiment, such as Figure 3 As shown:

[0035] The bottom of the mixing chamber 1 is provided with a powder brushing structure 13 for applying release agent to the mold plate 8. The design of the powder brushing structure 13 makes it convenient to apply release agent to the mold plate 8 when it passes by, for the purpose of demolding the pills from the mold plate 8, while preventing the pills from sticking together due to the stickiness of the drugs.

[0036] In addition, such as Figure 1-2 As shown:

[0037] A collection funnel 14 is fixed to the bottom of the mixing chamber 1. Supporting feet are fixed around the bottom of the mixing chamber 1 on the outside of the collection funnel 14. With the cooperation of the collection funnel 14, it is convenient to collect the pills that are demolded from the mold plate 8.

[0038] In practical use, the drug raw materials are added into the mixing chamber 1 through the feeding port. The second motor 11 is started, which drives the rotating shaft 5 to rotate. The rotating shaft 5 drives the stirring plate 12 to mix the raw materials. Then, the first motor 31 is started, which drives the stirring shaft 32 to drive the spiral blades 33. The spiral blades 33 carry the mixed raw materials from the upper end of the fixed cylinder 2 to the lower end, and discharge them from the discharge hole 4. The materials are squeezed into the mold plate 8 below. The mold plate 8 moves with the rotation of the rotating shaft 5. Then, when the rotating gear 93 contacts the arc-shaped rack plate 95, the rotating gear 93 rotates on the arc-shaped rack plate 95. The rotating shaft 7 drives one set of movable shafts 7 to rotate, and then the other set of movable shafts 7 rotates synchronously in the opposite direction under the cooperation of the adjusting gear 91 and the transition gear 92, so that the two sets of mold plates 8 are merged, and the drugs on the two sets of mold plates 8 are merged into a whole pill. When the rotating gear 93 separates from the arc-shaped rack plate 95, the torsion spring 10 rotates the two sets of movable shafts 7 in the opposite direction, so that the mold plates 8 are separated, and the internal pills fall into the collection funnel 14 below. At the same time, with the rotation of the rotating shaft 5, the mold plate 8 is transferred to the bottom of the powder brushing structure 13, and the surface of the mold plate 8 is brushed with a release agent to prevent the drug raw materials from sticking to the mold plate 8. The drug is periodically granulated.

[0039] Although embodiments of the present invention have been shown and described, it will be understood by those skilled in the art that various changes, modifications, substitutions and alterations can be made to these embodiments without departing from the principles and spirit of the present invention, the scope of which is defined by the appended claims and their equivalents.

Claims

1. A high-efficiency mixing and granulation machine for pharmaceutical use, comprising a mixing bin (1), characterized in that: The mixing chamber (1) has a feeding port at the top. A fixed cylinder (2) is fixed at the bottom of the inner cavity of the mixing chamber (1). The bottom of the fixed cylinder (2) passes through the mixing chamber (1) and extends downward. An extrusion assembly (3) for conveying drugs downward is provided inside the fixed cylinder (2). Multiple discharge holes (4) are provided at the bottom of the fixed cylinder (2). A rotating shaft (5) is rotatably connected to the center of the inner cavity of the mixing chamber (1) through a bearing. The bottom of the rotating shaft (5) passes through to the bottom of the mixing chamber (1) and is fixed with multiple connecting rods. A fixed frame (6) is fixed at the end of the connecting rod away from the rotating shaft (5). Two sets of movable shafts (7) are rotatably connected to the inner cavity of the fixed frame (6) through a bearing. A mold plate (8) is fixed on the outside of the movable shaft (7). An adjustment assembly (9) for closing the mold plate (8) is provided at the bottom of the mixing chamber (1).

2. The pharmaceutical high-efficiency mixing and granulation machine according to claim 1, characterized in that: The adjustment assembly (9) includes two sets of chambers opened inside the fixed frame (6). One end of the movable shaft (7) passes through one set of chambers and is fixed with an adjustment gear (91). The opposing side of the adjustment gear (91) is meshed with a transition gear (92). The transition gear (92) rotates in the chamber. The other end of the movable shaft (7) passes through the outside of the fixed frame (6) and is fixed with a rotating gear (93). The bottom of the mixing bin (1) is fixed with a connecting frame (94). The inner side of the connecting frame (94) is fixed with an arc-shaped rack plate (95) that meshes with the rotating gear (93).

3. The pharmaceutical high-efficiency mixing and granulation machine according to claim 1, characterized in that: The extrusion assembly (3) includes a first motor (31) fixed to the top of the fixed cylinder (2). The output shaft of the first motor (31) passes through the fixed cylinder (2) and is fixed with a stirring shaft (32). A spiral blade (33) is fixed to the outside of the stirring shaft (32). The top of the mold plate (8) is attached to the bottom of the fixed cylinder (2).

4. The pharmaceutical high-efficiency mixing and granulation machine according to claim 1, characterized in that: A torsion spring (10) is fixed to the outside of the movable shaft (7), and the end of the torsion spring (10) away from the movable shaft (7) is fixed to the fixed frame (6).

5. A high-efficiency mixing and granulation machine for pharmaceutical use according to claim 1, characterized in that: The top of the mixing silo (1) is fixed with a second motor (11). The output shaft of the second motor (11) passes through the inner cavity of the mixing silo (1) and is fixedly connected to one end of the rotating shaft (5). A stirring plate (12) is fixed on the outside of the rotating shaft (5).

6. The pharmaceutical high-efficiency mixing and granulation machine according to claim 1, characterized in that: The bottom of the mixing hopper (1) is provided with a powder brushing structure (13) for applying release agent to the mold plate (8).

7. The pharmaceutical high-efficiency mixing and granulation machine according to claim 1, characterized in that: The bottom of the mixing hopper (1) is fixed with a collection funnel (14), and the bottom of the mixing hopper (1) is fixed with support feet on the outside of the collection funnel (14).

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