A granulator for pharmaceutical use

Abstract

This utility model discloses a pharmaceutical granulator, belonging to the field of pharmaceutical granulation technology. A material inlet is formed between the barrel and a partition plate. A discharge port is located at the side opening of the material inlet. Granulated drug from the granulation through-hole falls into the material inlet and is then discharged from the discharge port. A mounting base is connected to the side wall of the drive shaft, and a rotary discharge plate is connected to the mounting base. The rotary discharge plate rotates at the material inlet via the drive shaft, accelerating the discharge of granulated drug from the material inlet to the discharge port. This pharmaceutical granulator, with its rotary discharge plate rotating via the drive shaft, accelerates drug discharge and improves production efficiency. Its arc-shaped edge design promotes smooth material discharge, prevents blockages, and ensures continuous and stable production. By adjusting the rotation speed and angle, material discharge can be precisely controlled, improving equipment flexibility and adaptability to meet diverse production needs. The arc-shaped design reduces material breakage and ensures product quality.

Description

Technical Field

[0001] This utility model relates to the field of pharmaceutical granulation technology, and in particular to a granulator for pharmaceutical use. Background Technology

[0002] A pharmaceutical granulator is a machine that compresses drug components into solid granules and is one of the key pieces of equipment in the production of solid dosage forms. In the pharmaceutical industry, granulators are crucial for drug granulation. Currently, most granulators achieve drug granulation through extrusion. Their working principle involves mixing drug powder with excipients, adding a binder to create a soft mass, and then using forced extrusion to force the soft mass through a sieve with a specific size, thereby forming granules. Such granulators typically have a cylinder connected to a discharge port to expel the produced granules.

[0003] However, in actual use, firstly, equipment malfunction is one of the main reasons for slow discharge speed in granulators. For example, damaged bearings may cause the rotor to rotate sluggishly, thus affecting the raw material's running speed in the hopper; gearbox misalignment will also affect the raw material conveying speed; prolonged use of blades will cause wear, resulting in inconsistent particle size and slower discharge speed. In addition, problems such as clogged vibrating screen holes and damaged drum structure can also lead to decreased granulation efficiency. Secondly, raw material quality issues can also affect the granulator's discharge speed. For example, excessively large particle size or excessive moisture content in the raw material can lead to low granulation efficiency. Overly large particles require more time and energy to crush and mix, while excessively moist raw materials may increase their adhesion, causing them to stick together in the hopper and thus affecting the discharge speed. Finally, improper operation can also lead to slow discharge speed in granulators. For example, excessively fast feeding speed or excessive pressure can cause equipment blockage, thus affecting the discharge speed. Utility Model Content

[0004] The main objective of this invention is to provide a granulator for pharmaceutical use, which can effectively solve the problems mentioned in the background art.

[0005] To achieve the above objectives, the technical solution adopted by this utility model is as follows:

[0006] A pharmaceutical granulator includes a housing, a drive unit, a transmission assembly, a drive shaft, a barrel, a disassembly cylinder, a partition plate, granulation through holes, and a rolling extrusion assembly. The transmission assembly is installed at the bottom of the housing, the drive unit is installed on the side wall of the transmission assembly, the drive shaft is installed at the top of the transmission assembly, the barrel is fixed to the housing, the disassembly cylinder is installed on the barrel by fasteners, the partition plate is installed at the opening of the barrel, and multiple granulation through holes are distributed on the partition plate. The drive shaft passes through the partition plate and connects to the rolling extrusion assembly. The rolling extrusion assembly drives the drug on the partition plate into the granulation through holes to achieve the granulation operation.

[0007] A material inlet is formed between the barrel and the partition plate. A discharge port is provided at the side wall opening of the material inlet. The granulating drug falls into the material inlet through the granulation through hole and is then discharged from the discharge port.

[0008] The drive shaft has a mounting base connected to its side wall, and a rotary discharge plate is connected to the mounting base. The rotary discharge plate rotates at the material inlet via the drive shaft, which speeds up the discharge of granulated drugs from the material inlet to the outlet.

[0009] In an optional embodiment of this application, two parallel base frames are installed at the lower end of the chassis, and the base frames are fixed to the chassis with bolts. A crossbar is provided at the upper end of the base frames. A bracket is provided on the crossbar to connect with the drive device, and the crossbar and bracket are used to support the drive device.

[0010] In an optional embodiment of this application, the output end of the drive device is connected to the gear set in the transmission assembly, the transmission assembly is connected to the transmission shaft, the transmission assembly is fixed to the chassis by screws and nuts, the transmission assembly includes a housing, and a bearing assembly is provided between the transmission shaft and the housing, the chassis, and the barrel;

[0011] In an optional embodiment of this application, the fasteners are fastening bolts, fastening nuts, and anti-slip washers. The side walls of the disassembly cylinder and the machine barrel are provided with rings. The fastening bolts are inserted into the two rings and then fixed by fastening nuts and anti-slip washers.

[0012] In an optional embodiment of this application, the isolation plate is fixed to the barrel with bolts, the granulation holes are evenly distributed on the isolation plate, the rolling extrusion assembly is designed in a dumbbell shape, the drive shaft is placed in the middle section of the rolling extrusion assembly, and the rolling extrusion assembly and the drive shaft are fixed.

[0013] In an optional embodiment of this application, the mounting base is embedded in the opening on the side wall of the drive shaft and welded to the drive shaft, and the rotary discharge plate is fixed to the drive shaft by bolts, with the edge of the rotary discharge plate having an arc-shaped design.

[0014] Compared with the prior art, the present invention has the following beneficial effects:

[0015] The rotary discharge plate rotates at the material inlet via a drive shaft, which helps to accelerate the discharge of granulated drugs from the material inlet to the outlet, significantly improving the production efficiency of the equipment.

[0016] The rotary discharge plate features an arc-shaped edge design, which facilitates smooth material discharge, preventing blockages and accumulation during the discharge process and ensuring continuous and stable production. By adjusting the rotation speed and angle of the rotary discharge plate, precise control over the material discharge speed and volume can be achieved, enhancing the equipment's flexibility and adaptability to meet diverse production needs.

[0017] The curved design of the rotary discharge plate not only helps the material to be discharged smoothly, but also reduces the damage of the material during the discharge process, thus ensuring the quality of the product. Attached Figure Description

[0018] Figure 1 This is a schematic diagram of the overall structure of this utility model;

[0019] Figure 2 This is a top view of the overall structure of this utility model;

[0020] Figure 3 This is a front view of the overall structure of this utility model;

[0021] Figure 4 The diagram shows the drive shaft, isolation plate, granulation through hole, rolling extrusion assembly, rotary discharge plate, and discharge port of this utility model.

[0022] In the diagram: 1. Base frame; 2. Chassis; 3. Drive unit; 4. Transmission assembly; 5. Drive shaft; 6. Barrel; 7. Disassembly cylinder; 8. Fastener; 9. Isolation plate; 10. Granulation through hole; 11. Rolling extrusion assembly; 12. Mounting base; 13. Rotary discharge plate; 14. Discharge port; 15. Material outlet. Detailed Implementation

[0023] To make the technical means, creative features, objectives and effects of this utility model easier to understand, the present utility model will be further described below in conjunction with specific embodiments.

[0024] like Figure 1 - Figure 4As shown, a pharmaceutical granulator comprises several key components, including a housing 2, a drive unit 3, a transmission assembly 4, a drive shaft 5, a barrel 6, a disassembly cylinder 7, a partition plate 9, granulation through-holes 10, and a rolling extrusion assembly 11. The transmission assembly 4 is carefully installed at the bottom inner part of the housing 2 to ensure stable operation. The drive unit 3 is mounted on the side wall of the transmission assembly 4 and provides power. The drive shaft 5 is mounted at the upper end of the transmission assembly 4, transmitting the power from the drive unit 3 to other components. The barrel 6 is fixed to the housing 2, ensuring precise control of the granulation process. The disassembly cylinder 7 is mounted on the barrel 6 using fasteners 8, facilitating maintenance and cleaning. The partition plate 9 is installed at the opening of the barrel 6, helping to isolate and control the flow of the drug. Multiple granulation through-holes 10 are evenly distributed on the partition plate 9; these through-holes are key channels for drug granulation. The drive shaft 5 passes through the partition plate 9 and is connected to the rolling extrusion assembly 11. The rolling extrusion assembly 11 drives the drug on the partition plate 9 into the granulation through hole 10 through its movement, thereby completing the granulation operation.

[0025] A material inlet 15 is formed between the barrel 6 and the partition plate 9, and a discharge port 14 is provided at the side opening of the material inlet 15. After the drug granulation at the granulation through hole 10 is completed, it will fall into the material inlet 15 and then be discharged from the discharge port 14, ensuring the smooth output of the drug.

[0026] A mounting base 12 is connected to the side wall of the drive shaft 5, and a rotary discharge plate 13 is connected to the mounting base 12. The rotary discharge plate 13 rotates at the material inlet 15 via the drive shaft 5, which helps to speed up the discharge of granulated drugs from the material inlet 15 to the discharge outlet 14, thereby improving production efficiency.

[0027] Two parallel base frames 1 are installed at the lower end of the chassis 2. The base frames 1 are fixed to the chassis 2 with bolts to ensure the stability of the equipment. A cross frame is provided at the upper end of the base frame 1. A bracket is installed on the cross frame and connected to the drive device 3. The cross frame and the bracket together support the drive device 3, ensuring the stable operation of the equipment.

[0028] The output end of the drive unit 3 is connected to the gear set in the transmission assembly 4, which in turn is connected to the drive shaft 5, ensuring smooth power transmission. The transmission assembly 4 is fixed to the housing 2 by screws and nuts. The transmission assembly 4 includes a housing, and bearing assemblies are provided between the drive shaft 5 and the housing, housing 2, and barrel 6. These bearing assemblies help reduce friction and improve the service life and operating efficiency of the equipment.

[0029] Fastener 8 consists of fastening bolts, fastening nuts, and anti-slip washers. The side walls of disassembly cylinder 7 and machine cylinder 6 are equipped with rings. The fastening bolts are inserted into the two rings and then fixed by fastening nuts and anti-slip washers. This design ensures the firmness of the connection and facilitates disassembly and maintenance.

[0030] The separator plate 9 is fixed to the barrel 6 by bolts, and the granulation through holes 10 are evenly distributed on the separator plate 9 to ensure the consistency and uniformity of drug granulation. The rolling extrusion assembly 11 has a dumbbell-shaped design, and the drive shaft 5 is placed in the middle section of the rolling extrusion assembly 11. The rolling extrusion assembly 11 and the drive shaft 5 are stably connected by a specific fixing method.

[0031] Mounting bracket 12 is embedded in the side wall opening of drive shaft 5 and welded to drive shaft 5, ensuring a firm connection between mounting bracket 12 and drive shaft 5. Rotary discharge plate 13 is fixed to drive shaft 5 with bolts. The edge of rotary discharge plate 13 is arc-shaped, which helps the material to be discharged smoothly and reduces the breakage of material during the discharge process.

[0032] Assembly Process: Place the casing 2 in a suitable position. Install the transmission assembly 4 at the bottom of the casing 2, ensuring its stability. Install the drive unit 3 on the side wall of the transmission assembly 4. Install the drive shaft 5 at the top of the transmission assembly 4, ensuring its connection to the drive unit 3. Fix the barrel 6 to the casing 2, ensuring its accurate positioning. Install the disassembly cylinder 7 onto the barrel 6 using fasteners 8, ensuring it is secure and easy to disassemble and clean. Fix the partition plate 9 to the opening of the barrel 6 with bolts. Distribute multiple granulation through holes 10 evenly on the partition plate 9. Pass the drive shaft 5 through the partition plate 9 and connect it to the rolling extrusion assembly 11, ensuring the rolling extrusion assembly 11 is stable. Form a material inlet 15 between the barrel 6 and the partition plate 9, and provide a discharge port 14 at the side wall opening. Connect the mounting base 12 to the side wall of the drive shaft 5, and connect the rotary discharge plate 13 through the mounting base 12. Install two parallel base frames 1 at the bottom of the casing 2 and fix them with bolts. Connect the output end of the drive unit 3 to the gear set in the transmission assembly 4. The transmission assembly 4 is secured to the housing 2 using screws and nuts. The disassembly cylinder 7 is secured to the cylinder 6 using fastening bolts, fastening nuts, and anti-slip washers. The rolling extrusion assembly 11 is designed in a dumbbell shape to ensure a stable connection to the drive shaft 5. The mounting base 12 is embedded into the opening in the side wall of the drive shaft 5 and welded in place. The rotary discharge plate 13 is secured to the drive shaft 5 using bolts.

[0033] In operation: Turn on the drive unit 3 to start the equipment. Place the drug raw material into the barrel 6. The drive unit 3 provides power, and the transmission shaft 5 transmits the power to the rolling extrusion assembly 11. The rolling extrusion assembly 11 drives the drug on the separator plate 9 into the granulation through-hole 10, completing the granulation operation. The granulated drug falls into the material inlet 15 and is discharged from the outlet 14 by the rotation of the rotary discharge plate 13. Monitor the equipment's operating status and adjust the parameters of the drive unit 3 and transmission assembly 4 as needed. Perform regular maintenance and cleaning of the equipment, especially disassembling the barrel 7 and the rolling extrusion assembly 11, to ensure normal equipment operation. After completing the production task, turn off the drive unit 3 to stop the equipment operation.

[0034] All standard parts used in this utility model can be purchased from the market, and irregular parts can be customized according to the description and drawings. The specific connection methods of each part adopt conventional methods such as bolts, rivets, and welding that are mature in the prior art. The machinery, parts and equipment adopt conventional models in the prior art, and the circuit connection adopts conventional connection methods in the prior art, which will not be described in detail here.

[0035] The above are merely preferred embodiments of this utility model, but the scope of protection of this utility model is not limited thereto. Any equivalent substitutions or modifications made by those skilled in the art within the scope of the technology disclosed in this utility model, based on the technical solution and inventive concept of this utility model, should be included within the scope of protection of this utility model.

Claims

1. A pharmaceutical granulator, comprising a housing (2), a drive unit (3), a transmission assembly (4), a drive shaft (5), a barrel (6), a disassembly cylinder (7), a partition plate (9), granulation through holes (10), and a rolling extrusion assembly (11), wherein the transmission assembly (4) is installed at the bottom of the housing (2), the drive unit (3) is installed on the side wall of the transmission assembly (4), the drive shaft (5) is installed at the upper end of the transmission assembly (4), the barrel (6) is fixed on the housing (2), the disassembly cylinder (7) is installed on the barrel (6) by fasteners (8), the partition plate (9) is installed at the opening of the barrel (6), a plurality of granulation through holes (10) are distributed on the partition plate (9), the drive shaft (5) passes through the partition plate (9) and is connected to the rolling extrusion assembly (11), and the rolling extrusion assembly (11) drives the drug on the partition plate (9) into the granulation through holes (10) to realize the granulation operation, characterized in that: A material inlet (15) is formed between the barrel (6) and the partition plate (9), and a discharge port (14) is provided at the side wall opening of the material inlet (15). The granulating drug at the granulation through hole (10) falls into the material inlet (15) and is discharged from the discharge port (14). The side wall of the drive shaft (5) is connected to a mounting base (12), and a rotary discharge plate (13) is connected through the mounting base (12). The rotary discharge plate (13) rotates at the material inlet (15) through the drive shaft (5) to accelerate the discharge of granulated drugs from the material inlet (15) to the discharge outlet (14).

2. A granulator for pharmaceutical use according to claim 1, characterized in that: The lower end of the chassis (2) is equipped with two parallel base frames (1). The base frames (1) are fixed to the chassis (2) by bolts. The upper end of the base frame (1) is provided with a cross frame. A bracket is provided on the cross frame and connected to the drive device (3). The cross frame and the bracket are used to support the drive device (3).

3. A granulator for pharmaceutical use according to claim 2, characterized in that: The output end of the drive device (3) is connected to the gear set in the transmission assembly (4). The transmission assembly (4) is connected to the transmission shaft (5). The transmission assembly (4) is fixed to the housing (2) by screws and nuts. The transmission assembly (4) includes a housing. A bearing assembly is provided between the transmission shaft (5) and the housing, the housing (2), and the barrel (6).

4. A granulator for pharmaceutical use according to claim 3, characterized in that: The fasteners (8) are fastening bolts, fastening nuts and anti-slip washers. The side walls of the disassembly cylinder (7) and the machine cylinder (6) are provided with rings. The fastening bolts are inserted into the two rings and then fixed by fastening nuts and anti-slip washers.

5. A granulator for pharmaceutical use according to claim 4, characterized in that: The isolation plate (9) is fixed to the barrel (6) by bolts. The granulation through holes (10) are evenly distributed on the isolation plate (9). The rolling extrusion assembly (11) is designed in a dumbbell shape. The drive shaft (5) is placed in the middle section of the rolling extrusion assembly (11) to fix the rolling extrusion assembly (11) and the drive shaft (5).

6. A granulator for pharmaceutical use according to claim 5, characterized in that: The mounting base (12) is embedded in the side wall opening of the drive shaft (5) and welded to the drive shaft (5). The rotary discharge plate (13) is fixed to the drive shaft (5) by bolts. The edge of the rotary discharge plate (13) is arc-shaped.

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