Genetic modification of mammalian cells to confer resistance to CSF1R antagonists

DE202022003132U1Active Publication Date: 2025-03-27RGT UNIV OF CALIFORNIA
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Patent Information

Application Number
DE202022003132
Authority / Receiving Office
DE · DE
Patent Type
Utility models
Current Assignee / Owner
Priority Date
2021-08-25
Filing Date
2022-04-01
Publication Date
2025-03-27
Estimated Expiration
2032-04-30
Patent Text Reader

Abstract

Modified human cell comprising a modified CSF1R protein that exhibits resistance to a CSF1R antagonist, wherein the modified CSF1R protein includes a modified ATP-binding pocket capable of binding ATP.
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