TETRACYCLINE COMPOUNDS
Patent Information
- Application Number
- DE602013086620
- Authority / Receiving Office
- DE · DE
- Patent Type
- Patents
- Current Assignee / Owner
- Priority Date
- 2012-08-31
- Filing Date
- 2013-08-30
- Publication Date
- 2025-03-26
- Estimated Expiration
- Not applicable · inactive patent
AI Technical Summary
The widespread use of tetracyclines in medicine has led to the emergence of resistance among bacterial species, necessitating the development of new tetracycline analogs with improved antibacterial activities and efficacies against tetracycline-responsive diseases or disorders.
A compound represented by Structural Formula (I) or its pharmaceutically acceptable salt, which can be used in pharmaceutical compositions for treating and preventing bacterial infections, is disclosed. This compound has various substituents that can form carbocyclyl or heterocyclyl rings, offering enhanced antibacterial properties.
The compound demonstrates improved antibacterial activities against resistant bacterial strains and is effective in treating a range of tetracycline-responsive diseases, including infections and inflammatory disorders, while minimizing resistance development.