Chemical vapor deposition device with adhesion breaking capability and method of use thereof

By using agitated devices to manage particle distribution and prevent aggregation in ALD systems, the challenges of particle adhesion and uneven coatings are addressed, leading to improved coating uniformity and reduced product loss.

JP2025507980APending Publication Date: 2025-03-21VITRIVAX INC +1
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Patent Information

Application Number
JP2024552655
Authority / Receiving Office
JP · JP
Patent Type
Applications
Current Assignee / Owner
Priority Date
2022-04-29
Filing Date
2023-03-03
Publication Date
2025-03-21

AI Technical Summary

Technical Problem

In chemical vapor deposition systems, such as those used in atomic layer deposition (ALD), particles or microparticles tend to aggregate and adhere to the reactor walls and filters, leading to uneven coatings, product loss, and reduced coating uniformity.

Method used

The implementation of agitated devices, including vibration, shock, and sonication, in communication with the reactor vessel to maintain particle distribution, reduce aggregation, and prevent adhesion of particles or microparticles within the reactor system.

Benefits of technology

This approach effectively maintains the distribution of particles, reduces aggregation and adhesion, resulting in more uniform coatings, reduced product loss, and improved manufacturing efficiency.

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Abstract

The embodiments disclosed herein relate to a modified reactor system for making coated particles of a thermostable drug with reduced losses and improved coating uniformity due to avoidance of particle adhesion to the reactor or other particles. In certain embodiments, the reactor system includes a reaction vessel configured to receive particles of a thermostable drug, and one or more stirring attachments or devices including at least one of an ultrasonic agitator, a mechanical impactor, and a low-frequency vibrator directly connected or in fluid communication with the reactor system to sonicate, impact, or vibrate the reaction vessel during the particle coating process. In some embodiments, the reactor system includes a gas phase injection system configured to introduce alternating pulses of a chemical vapor material into the reaction vessel to form a coating on the particles while continuously or intermittently stirring the reactor system.
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