Methods for detecting rheumatoid arthritis

Abstract

To provide a novel detection method for rheumatoid arthritis. [Solution] The present invention provides a method for detecting rheumatoid arthritis, comprising the step of determining the presence of rheumatoid arthritis using the amount or concentration of autoantibodies against citrullinated proteins (citrullinated protein autoantibodies) in a target biological sample as an indicator, wherein the citrullinated protein autoantibodies are (1) citrullinated RBMXL2 autoantibodies and / or (2) citrullinated CDKN1C autoantibodies. The present invention is advantageous in that it allows for the simple and accurate detection of rheumatoid arthritis. Furthermore, the present invention is advantageous in that it can detect rheumatoid arthritis even in subjects that are difficult to detect with conventional biomarkers, and in that it has higher accuracy than conventional biomarkers in detecting rheumatoid arthritis.