eye drop container

The laminate structure of cyclic olefin copolymer and polyethylene resin in eye drop containers addresses the issues of high squeeze strength and sorption/evaporation by improving non-sorption and moisture resistance, ensuring easier administration and extended shelf life.

JP7763396B2Active Publication Date: 2025-11-04ZACROS CORP
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Patent Information

Application Number
JP2020560084
Authority / Receiving Office
JP · JP
Patent Type
Patents
Current Assignee / Owner
Priority Date
2018-12-07
Filing Date
2019-12-06
Publication Date
2025-11-04
Estimated Expiration
2039-12-06

AI Technical Summary

Technical Problem

Conventional eye drop containers made of cyclic olefin copolymers face issues with high squeeze strength due to their hardness, leading to difficulty in administering drops, and they also suffer from sorption and evaporation of active ingredients.

Method used

A laminate structure is used for the eye drop container, comprising a layer of cyclic olefin copolymer with a polyethylene resin on the outside, where the cyclic olefin copolymer layer has a thickness of 50 to 1000 μm, and the laminate thickness ranges from 300 to 2000 μm, enhancing non-sorption and moisture resistance while reducing squeeze strength.

Benefits of technology

The laminate structure effectively suppresses sorption and evaporation of eye drops, improves moisture resistance, and reduces squeeze strength, thereby enhancing squeezability and shelf life.

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Abstract

This eye drop container (30) has a storage section (31) for storing eye drops, and the storage section (31) is made of a laminate having a layer containing a cyclic olefin copolymer and a layer containing a polyethylene resin provided outside the layer containing the cyclic olefin copolymer. The thickness of the layer containing the cyclic olefin copolymer is 50 to 1000 μm, and the thickness of the laminate is 300 to 2000 μm. This container can suppress sorption (adsorption, absorption) of eye drops, improve moisture resistance to suppress evaporation, and further reduce squeeze strength.
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