Lateral flow test device
The lateral flow test device addresses the need for a POC nucleosome detection method by using a substrate with capture reagents and a conjugate pad with labelled detection reagents, enabling rapid and accurate nucleosome detection for improved disease diagnosis and monitoring.
Patent Information
- Application Number
- PCT/EP2024/076281
- Authority / Receiving Office
- WO · WO
- Patent Type
- Applications
- Current Assignee / Owner
- Priority Date
- 2023-09-19
- Filing Date
- 2024-09-19
- Publication Date
- 2025-03-27
AI Technical Summary
There is a need for a point-of-care (POC) test to detect nucleosomes for real-time diagnosis and monitoring of patients, particularly in conditions associated with rapid decline such as sepsis, where timely detection is critical.
A lateral flow test device is developed for detecting target nucleosomes in a sample, comprising a substrate with a test location containing a capture reagent and a conjugate pad with a labelled detection reagent that binds to the nucleosomes, allowing for a visible signal indicating their presence.
The lateral flow test device enables rapid and accurate detection of nucleosomes, facilitating early disease diagnosis and monitoring, particularly in POC settings, thereby improving patient outcomes by allowing for timely intervention.