Precision ultrasound apparatus using electrode arrangement for electroencephalography

The precision ultrasound device with EEG electrode placement effectively targets brain regions to enhance cerebrospinal fluid circulation and waste removal, addressing the risks of conventional methods while improving safety and efficacy for conditions like Alzheimer's disease.

WO2026127593A1PCT designated stage Publication Date: 2026-06-18DEEPSONBIO CO LTD
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Patent Information

Authority / Receiving Office
WO · WO
Patent Type
Applications
Current Assignee / Owner
DEEPSONBIO CO LTD
Filing Date
2025-12-09
Publication Date
2026-06-18

AI Technical Summary

⚠Technical Problem

Conventional ultrasound techniques for stimulating the brain risk cerebral hemorrhage due to excessive disruption of the blood-brain barrier and are ineffective for specific brain region targeting, especially for promoting cerebrospinal fluid circulation and waste removal, and are uncomfortable with multiple wires.

⚗Method used

A precision ultrasound device using EEG electrode placement with dual frequency generators, modulators, amplifiers, and transducers to precisely target brain regions, inducing volumetric flow and promoting cerebrospinal fluid circulation and waste removal through the cerebral lymphatic system.

🎯Benefits of technology

Enhances the movement of brain waste products like amyloid beta and tau protein into the perivascular space, increasing cerebrospinal fluid circulation and minimizing side effects, thus benefiting conditions like Alzheimer's disease and stroke.

✦ Generated by Eureka AI based on patent content.

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Abstract

The present invention relates to a precision ultrasound apparatus using an electrode arrangement for electroencephalography (EEG), in which ultrasound transducers are precisely arranged and characteristics of ultrasound are adjusted by using an EEG device, thereby enabling effective targeting of a specific region in a ventricle of a brain. To this end, the apparatus comprises: a first frequency generation unit (210); a first waveform modulator (230) for modulating the waveform of a first frequency; a first linear amplifier (250) for amplifying the waveform of the first frequency; a first resonant circuit unit (170a) for matching the impedance of an amplified waveform of the first frequency; first ultrasound transducers (100), connected to the first resonant circuit unit (170a), for irradiating ultrasound (30) toward a brain (10) of a mammal; a second frequency generation unit (310); a second waveform modulator (330) for modulating the waveform of a second frequency; a second linear amplifier (350) for amplifying the waveform of the second frequency; a second resonant circuit unit (170b) for matching the impedance of an amplified waveform of the second frequency; and second ultrasound transducers (200), connected to the second resonant circuit unit (170b), for irradiating ultrasound (30) toward the brain (10) of the mammal, wherein the plurality of first ultrasound transducers (100) and the plurality of second ultrasound transducers (200) are provided at the positions of electrodes (120) of a headgear (20) having an electrode arrangement for electroencephalography.
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