A beam homogenizer shapes side-entry illumination through a prism to uniformly excite only the well bottom, reducing speckle and autofluorescence.
Machine learning analyzes neighboring partition fluorescence to detect digital PCR leakage faster and improve assay accuracy.
Logicle preprocessing and FlowSOM clustering handle multicolor flow cytometry data growth while reducing misclassification and analysis time.
Compressed flow cytometry data is linked back to original fluorescence measurements, enabling faster cell clustering with result verification.
Regional and patch embeddings improve weakly labeled whole-slide pathology classification without time-consuming patch-level annotation.
Unsupervised analysis of nuclear morphology and cell image features identifies senescent cells more consistently across tissues and contexts.
Calculated dark-field illumination angles prevent secondary reflections in specimen carriers, enabling clear unstained cell nucleus imaging.
Uniformly reduced contour coordinates keep whole slide target images within size limits while preserving contour spacing and accuracy.
Defocused or lensless CNN imaging tracks sperm positions across image series to characterize motility and morphology with wide field coverage.
Live-cell label-free imaging and machine learning classify macrophage polarization states in real time, reducing invasive, slow wet lab assays.
Logicle conversion and FlowSOM batch learning improve multicolor flow cytometry clustering accuracy while reducing spectral misclassification.