Bacteria TRIZ Cases

Recombinant Bacillus subtilis integrates multiple galactotransferase genes to boost enzyme activity and resolve low yield constraints.

Inorganic nanoparticle-microorganism complexes produce ammonia at ambient conditions using light irradiation.

Modified cyanobacteria express exogenous diacylglycerol acyltransferase and phosphatidate phosphatase to synthesize triglycerides.

An expression vector fuses target membrane proteins with the Cystovirus phi6 P9 envelope protein to enable effective cellular production.

A process converts waste textile cellulose into glucose using controlled NaOH and urea pre-treatment followed by enzymatic saccharification.

An engineered Escherichia strain inactivates degradation genes to maintain high GMP accumulation during fermentation.

NCgl2954 gene mutation enhances xylose uptake in coryneform bacteria, resolving low assimilation efficiency with inexpensive carbon sources.

Reinforced Clostridial Medium with neutral red and antibiotics reduces detection time while eliminating false positives from accompanying flora.

Blautia strains induce interleukin production to resolve the contradiction between symptom relief and prevention effectiveness in rhinovirus infections.

Increasing pH triggers spontaneous gelation in cyanobacterial polysaccharides, simplifying recovery and reducing production costs.

A dcm- bacterium prepares methylated nucleic acid molecules for stable integration into Clostridia hosts.

Replacing E. coli curli with Bacillus subtilis TasA secretion enables large protein diversity and precise 3D printing of complex geometries.

A recombinant Escherichia coli strain co-expresses four enzymes to catalyze the whole-cell transformation of aromatic amino acids into phenylethanoids.

Hybridoma cell strain CGMCC No. 18317 secretes monoclonal antibody Ts-ZH68-2A4-Ab targeting serine protease antigens.

Amycolatopsis sp. strain zhp06 converts ferulic acid to vanillin, eliminating chemical synthesis pollution while maintaining high purity.

Lactobacillus plantarum PS128 prevents exercise-related muscle damage and kidney injury by modulating immune responses to enhance physical performance.

Biological fermentation converts biodegradable feedstocks into pure carboxylic acid salts.

Bacteroides intestinalis strains treat obesity and diabetes by reducing body weight and blood glucose without conventional drug side effects.

Isolated Pseudomonas silesiensis strain degrades sulfamethoxazole via extracellular polymers, resolving complexity issues in bioelectrochemical wetlands.

Biotin-modified monoclonal antibodies coupled to streptavidin-coated magnetic beads specifically capture complete virus particles for downstream PCR analysis.

Engineering Vibrio natriegens Aly01 for extracellular secretion in E. coli simplifies downstream processing and eliminates cell disruption steps.

Links exogenous toxin genes to regulatable promoters with cognate antitoxins to prevent uncontrolled microbial spread.

Introducing an epi-type ketoreductase gene into a daunorubicin-producing bacterium overcomes low yield and high cost of chemical synthesis.

Secreted fungal catalase degrades hydrogen peroxide in growth media to maintain enzyme stability during production and storage.

Novel sucrose permease polypeptides transport sucrose into metabolically engineered cells to boost glycosylated product yields.

Strains isolated from Camellia sinensis reduce toxic D-lactic acid while maintaining superior intestinal viability.

Lactobacillus brevis ProGA28 metabolites reduce rapid eye movement sleep phase time and increase total sleep duration.

Deleting the metE gene and overexpressing metH in recombinant microorganisms improves methionine carbon source yield while reducing production costs.

Sugar efflux transporter proteins export oligosaccharides from bacterial cells, preventing intracellular accumulation and cytotoxicity.

Segmented transforming DNA and an integrase mediator enable precise site-specific integration, resolving low uptake efficiency in plant nuclear transformation.

Engineered bacterial epimerase converts intracellular GlcNAc-6-P to ManNAc-6-P for efficient glycoconjugate sialylation.

Engineered Salmonella vectors deliver antigens to newly hatched chicks while undergoing controlled self-destruction to prevent environmental persistence.

A decolorizing composition uses dicyandiamide and hydrogen peroxide to remove fermentation dyes from pectate lyase solutions.

Modifying PerR gene expression creates oxygen-tolerant Megasphaera elsdenii strains that resolve shelf life instability caused by oxygen sensitivity.

High-protein culture media boosts amino acid profiles while reducing bitter and beany tastes in vegetarian protein sources.

Engineering Corynebacterium with weakened SugR and enhanced GltA increases putrescine yield while lowering energy consumption compared to chemical synthesis.

A culture medium combines chromogenic substrates to detect specific bacterial enzymes and differentiate Listeria species by colony color.