Bacteria TRIZ Cases

Lactobacillus fermentum LM1016 strain reduces C-reactive protein, neutral fat, and cholesterol concentrations.

Steel slag and Bacillus subtilis microcapsules solidify sludge via carbonation, reducing energy consumption while decomposing organic pollutants.

Starch hydrolysate, glutamic acid salt, and polyol maintain over 50% bacterial viability after six months storage at 25°C without animal-derived compounds.

Leuconostoc citreum WiKim0104 reduces liver fat by 35 percent while avoiding the side effects of synthetic pharmaceuticals.

A fermentation process enhances 2,3-butanediol production using acetogenic microorganisms.

Expressing vanillate demethylase and 3,4-dioxygenase in Pseudomonas putida overcomes limited S-lignin metabolism capacity for efficient PDC production.

Engineered oleaginous bacteria express cellulolytic enzymes to hydrolyze cellulosic substrates directly into lipids.

Inorganic polyphosphate-based energy regeneration sustains ATP levels through AdK and PPK enzymes, extending reaction duration and increasing protein yields.

Internal hydrogen generation via microbial culture eliminates mechanical stirring risks while maintaining uniform distribution and optimal redox potential.

Reductive catalytic fractionation breaks down lignin structure to boost aromatic monomer yields, overcoming low efficiency in traditional conversion methods.

Charged amino acid substitution restricts side chain repacking to stabilize allosteric proteins in specific conformational states.

Engineered E. coli expressing YahK converts xylose to xylitol, bypassing harsh chemical synthesis conditions.

Lactobacillus salivarius LS97 prevents dental caries by antagonizing Streptococcus sobrinus without inducing drug resistance.

Engineered microbes convert syngas to chemicals, overcoming low yield and poor genetic manipulability of native Clostridium strains.

Deleting mgsA, pfl, and adh genes in thermophilic bacteria eliminates by-products to achieve 98% chiral purity.

Engineered Thermococcus onnurineus MC02 strain with increased rchA gene expression produces hydrogen from carbon monoxide.

Constant rate inducer feeding maintains specific growth rates to prevent by-product accumulation and boost yields.

Engineered Pichia ciferrii cells accumulate high titers of acetylated sphingoid bases without antibiotic selection pressure.

Optimized compression preserves bacteria in stable tablets, preventing feeder jamming and equipment damage.

Mutant DNA polymerases with specific amino acid substitutions increase reverse transcriptase efficiency for RNA amplification.

Recombinant E. coli strain increases intracellular ATP levels through genetic modification of specific proteins.

Cre-lox recombination removes selection markers from Deinococcus radiodurans, bypassing time-consuming cloning steps to enable high-yield phytoene production.

Complex coacervates of octenyl succinic anhydride starch and chitosan shield microbial cultures during processing.

Applying a plant-derived lactobacillus treatment to manure lowers ammonia and sulfide emissions without harsh chemicals.

Auxotrophic markers replace antibiotic resistance to eliminate environmental harm while maintaining selection reliability.

Modified Corynebacterium strain produces putrescine by blocking the ornithine to arginine biosynthetic pathway and introducing ornithine decarboxylase.

Variant GlcT proteins in modified Bacillus cells boost protein yield while maintaining fermentation stability.

Engineered bacterial host cells convert glycerol and volatile fatty acids into poly(3-hydroxybutyrate-co-3-hydroxyvalerate) using specific catalytic proteins.

Myristic acid compounds inhibit Gram-negative bacteria in the enrichment medium, resolving competitor interference for accurate Listeria detection.

Novel fucosyltransferases transfer fucose residues to lactotetraose substrates.

Superparamagnetic iron particles bind target peptides to capture pathogens, reducing concentration by 99.95% for faster sepsis diagnosis.

Fermenting bacterial concentrates increases cell surface hydrophobicity to stabilize frozen or dry prokaryotic compositions.

Standardized Lactobacillus kefiri SGL 13 composition resolves inconsistent kefir fermentation to reduce intestinal inflammation.

Engineered E. coli strains produce fusel lactates via enzymatic esterification, replacing energy-intensive chemical synthesis with sustainable biocatalysis.

Lactobacillus fermentum CQPC04 modulates coagulation and inflammatory markers to inhibit thrombus formation.

Lactobacillus paragasseri BBM171 shifts Th2 to Th1 responses, reducing inflammatory cell infiltration and mucus production.

Rhizobia species introduce nucleic acids into plant cells via VirD2-dependent or traA-independent mechanisms.

Targeted amino acid substitutions at positions 162 and 230 enhance pepsin resistance, acid stability, and catalytic efficiency by up to 2.4 times.

Compatible restriction sites allow polynucleotide transfer between ribosome and phage display systems, overcoming bacterial transformation efficiency limits.

Food-grade bacteria sequester and degrade glyphosate, replacing costly chemical cleanup with scalable biological remediation.

Measuring lactic acid bacteria binding to uromodulin protein replaces time-consuming animal models with rapid in vitro screening.

Acid clay adsorbs antibacterial substances from microbial culture media to support target bacterium growth.

Psychrophilic bacteria formulations solubilize phosphorus at 0°C, addressing low-temperature deficiency in cold soils.

A heat-killed Lactobacillus rhamnosus conjugate bound to a polysaccharide polymer binder enhances adhesion to intestinal mucosal immune cells.

Modified Corynebacteria strains utilize glycerol through introduced GlpDFK genes for amino acid production.

Integrating SV40 enhancers into plasmid backbones resolves the trade-off between high production yield and product purity in bacterial fermentation cultures.

A recombinant microorganism uses Ilyobacter polytropus glycerol dehydratase to produce 3-hydroxypropionic acid.

Genetically engineered bacteria with modified glnD genes increase nitrogen fixation rates in non-leguminous crops.