Saponin-based adjuvants boost pneumococcal conjugate vaccines to broaden serotype protection and strengthen opsonophagocytic responses.
Selected TB antigens in mRNA lipid nanoparticles broaden T cell targeting across MHC diversity and strengthen protective immune responses.
A petrolatum carrier stabilizes liquid mucosal vaccines against heat excursions, extending ambient storage without potency loss.
Sequential autoclave heating modifies aluminum salt particles to boost antigen adsorption, immunogenicity, and vaccine safety.
Engineered lactic acid bacteria express allergen proteins to induce antibodies against dust mite and cockroach allergies when exposure control falls short.
Metal ions adsorbed on a microemulsion surface improve antigen uptake and lymph node delivery while keeping subunit vaccines stable and safer.
Copper-free cycloalkyne saccharide conjugation enables site-specific triazole linking, improving conjugate uniformity and vaccine immunogenicity.
Immunogenic HylA peptides trigger targeted immunity against C. acnes, reducing acne severity without broad microbiota disruption.
Attenuated recombinant Edwardsiella vectors enable bath vaccination in fish while preserving immune protection and limiting antibiotic resistance spread.
Using 18C glycoconjugates to trigger antibodies against 18A, 18B, and 18F, this case expands serogroup 18 coverage without adding more conjugates.