Bacterial Antigen Ingredients TRIZ Cases
- Oral Vaccine Applicator With Flexible Stem and Soft Tip
A flexible stem, soft tip, and resilient reservoir enable rapid oral animal vaccination with lower anxiety, safer handling, and low residual volume.
- Bacterial Polysaccharide Oxidation for Sizing and Purification
H2O2 treatment simultaneously fragments and purifies bacterial polysaccharides, cutting impurities while preserving vaccine-relevant structure.
- Canine Multivalent Vaccine for Leptospira Cross-Protection
A multivalent canine vaccine using non-Grippotyphosa serovars broadens protection to Grippotyphosa and reduces leptospirosis symptoms.
- Multivalent Canine Leptospira Vaccine for Icterohaemorrhagiae Cross-Protection
A multivalent canine vaccine using non-Icterohaemorrhagiae serovars induces cross-protection and reduces leptospirosis symptoms.
- Matrix-Bound Vesicle Adjuvants for Low-Toxicity Vaccination
Matrix-bound vesicles boost vaccine immune response and antibody production while avoiding the toxicity, granulomas, and abscesses linked to traditional adjuvants.
- CAMP-Targeted Recombinant Protein Vaccine for Acne Inflammation
Targeting the C. acnes CAMP virulence factor, this recombinant vaccine induces specific immunity to curb inflammation without broad antibiotic drawbacks.
- Recombinant C. Difficile Fusion Antigens for Stronger Neutralization
A scaffold-plus-repeat fusion antigen boosts C. difficile toxin neutralization 10-100 fold while remaining suitable for large-scale manufacture.
- Microorganism strain <i>Pediococcus acidilactici </i>tak 589 coccobest as an antimicrobial and antioxidant probiotic
A lyophilized Pediococcus acidilactici strain suppresses gut pathogens and oxidative stress while remaining active across pH and temperature changes.
- Modified BCG Vaccine for TB Protection Without Diagnostic Interference
Deleted antigen genes let a modified BCG vaccine preserve TB protection while avoiding interference with standard skin tests.
- Short-Lived Engineered Bacteria for Therapeutic Action Without Pathogenesis
Engineered live bacteria are given a built-in short lifespan to deliver therapeutic effect, then die to limit pathogenesis risk.
- Bladder-Delivered FimH Nanoparticle Vaccine for Recurrent UTI Immunity
Local bladder delivery of a FimH nanoparticle vaccine with Th1-skewing adjuvants boosts bacterial clearance and helps prevent recurrent UTIs.
- Single-Vial Lyophilized Vaccine Formulation for Thermostability
A lyophilized single-vial vaccine uses metabolizable oil and cake-forming excipients to stay stable without cold-chain storage.
- Microbiota Peptide Analogs for Tumor Antigen Vaccination
Microbiota-derived peptide analogs prime cross-reactive T cells against tumor antigens while helping limit immune tolerance and autoimmunity.
- Adjuvant-Free Streptococcal Vaccine Composition for Broad Serotype Immunity
An adjuvant-free streptococcal vaccine uses inactivated bacteria and PsaA expression to broaden serotype coverage while reducing side effects.
- Site-Directed fHBP Lipoprotein Conjugation for Broader MenB Vaccines
Unnatural amino acid insertion and click-linked liposomes enable uniform fHBP lipidation, broader MenB coverage, and fewer side effects.
- fHbp Fusion Vaccine Composition With Reduced OMV Reactogenicity
Combining fHbp v1, v2, and v3 in one antigen with lower OMV content broadens meningococcal coverage and reduces fever on co-administration.
- Fusion Polypeptide Vaccine Using Toxin A/B Binding Domains
A fused toxin A and toxin B receptor-binding polypeptide improves CDAD vaccine protection while avoiding full-toxin stability and yield issues.
- Fusion Protein Mhp Subunit Vaccine for Long-Term Swine Protection
A fusion protein antigen with ISA201VG emulsion extends Mhp subunit vaccine protection in pigs while simplifying safer administration.
- Lyophilised Chicken Intestinal Extract for In Ovo Gut Microbiota Establishment
In ovo delivery of lyophilised adult chicken intestinal extract helps establish gut microbiota before hatching, improving immunity and pathogen resistance.