Biological Material Analysis TRIZ Cases
- Saliva Pretreatment Filtration for Sensitive Immunochromatographic Tests
A porous member, 0.1-10 μm filtration, and target concentration remove saliva viscosity and boost sensitive SARS-CoV-2 detection.
- APC Reporter Screening for Cytotoxic T Cell Epitope Discovery
Engineered APCs with Granzyme B reporters and CAD inhibition enable sensitive, high-throughput discovery of cytotoxic lymphocyte antigens.
- EBV-Reactive CDR3 Profiling for Cancer Survival Prediction
Chemical complementarity scoring of TIL-derived CDR3 sequences links EBV reactivity with survival and treatment response in EBV-positive cancers.
- Broadly Neutralizing Antibodies Targeting the S2 Stem Helix
Targeting the conserved S2 stem helix helps antibodies avoid RBD mutation escape while maintaining broad neutralization across betacoronaviruses.
- Multiwell Lipophilicity Assay Using Membrane-Based Phase Separation
A lipophilic membrane in a sealed multiwell plate speeds equilibrium and avoids solvent separation for faster lipophilicity testing.
- Blood Analysis Using CRP and Particle Volume for Malaria Detection
CRP values and particle volume frequency peaks enable lower-cost malaria screening with reliable blood analysis using existing measurement functions.
- Composition, aqueous solution of endocrine protein, adsorption inhibitor, method for suppressing adsorption of endocrine protein, method for measuring amount of endocrine protein, and reagent kit for measuring endocrine protein
Combining fluorinated surfactants, collagen peptides, and milk proteins limits container adsorption and keeps endocrine protein standards accurate.
- Lectin Lateral-Flow Assay for Microbial Detection in Oily Liquids
An aqueous extraction plus calcium-rich MBP lateral-flow assay overcomes hydrophobic interference to detect microbial contamination in oily liquids.
- IL-8 Blood Assay for High-Grade Prostate Cancer Triage
Using IL-8 in blood with PSA improves discrimination of aggressive prostate cancer, helping avoid unnecessary biopsies and overtreatment.