Digestive System TRIZ Cases
- PD-1 Blockade for MSI Colorectal Cancer
Anti-PD-1 antibody therapy targets microsatellite instability tumors, improving survival in patients with high mutational burdens.
- OST-01 Phytochemicals for Cancer Treatment
OST-01 phytochemicals inhibit cancer cell proliferation and stimulate immune activity while reducing toxicity to healthy tissues.
- Fully Human ADCs Targeting 161P2F10B for Cancer Therapy
Fully human antibodies bind 161P2F10B to inhibit cancer growth while avoiding immune responses.
- Saroglitazar Composition for Hepatocellular Carcinoma Treatment
Formula I compounds reduce liver tumor incidence and serum injury markers, addressing inadequate treatment options for rising HCC cases.
- Human Dental Pulp Stem Cell Composition for Liver Tissue Regeneration
Differentiated human dental pulp stem cells administered via splenic sinus overcome temporary CD34-positive cell limitations.
- Synbiotic Formulation with Human Milk Oligosaccharides for Gut Health
A synbiotic supplement combines human milk oligosaccharides with probiotics to promote beneficial gut bacterial growth.
- Schinus terebinthifolius Extract for Digestive Disorder Treatment
Hydroalcoholic Schinus terebinthifolius extract isolates gallic acid and tannins to form a pharmaceutical composition.
- Adipose-Derived Stem Cells for Irradiated Skin Regeneration
Stromal vascular fraction cells accelerate keratinocyte differentiation and collagen production to promote skin regeneration.
- Moutan Cortex Radicis Extract Fraction for Liver Disease Treatment
Ethyl acetate fraction of Moutan Cortex Radicis extract reduces blood ALT concentration and prevents lipid peroxidation to treat liver disease.
- mARC1 Inhibitors for Lipid Metabolism Disorders
Inhibiting mARC1 replaces poor-compliance lifestyle interventions with targeted pharmaceutical therapy for obesity and fatty liver disease.
- Amprenavir Mitigates Aflatoxin B1 Liver Injury
Amprenavir blocks CYP450 enzymes to prevent DNA adducts, resolving inadequate countermeasures for public health threats.
- Apple Juice Bioactive Fraction Isolation via Electromagnetic Treatment
Electromagnetic wave treatment removes patulin and protein from apple juice, producing stable bioactive fractions for cosmetic and oral applications.
- RXR Agonist Drug for Lower GI Targeting
RXR agonist compound targets lower gastrointestinal tract while resisting upper tract absorption to reduce blood triglyceride levels.
- Monomethyl Fumarate Enteric Capsule Gastrointestinal Tolerability
Enterically coated monomethyl fumarate capsules deliver immediate-release liquid formulations to reduce gastrointestinal adverse events.
- Combination Therapy for Hepatitis B Using Phosphorothioated Nucleic Acid Polymers
Phosphorothioated nucleic acid polymers remove HBsAg from blood while nucleoside analog inhibitors block cccDNA replenishment in infected hepatocytes.
- THR-β Agonist Dosing via SHBG Biomarker Testing
A THR-β agonist treatment method uses baseline and benchmark SHBG biomarker tests to determine precise dosages for liver disorder management.
- Polysiloxane and Essential Oil Composition for Digestive Relief
A pharmaceutical preparation combining polysiloxane with peppermint, anise, fennel, and caraway oils to alleviate digestive discomfort.