DsDNA Viruses TRIZ Cases
- AAV Hollow Particle Encapsulation Without Capsid Denaturation
Linear AD-sequence fragments enable nucleic acid loading into empty AAV particles without denaturation, preserving infectious activity and lowering cytotoxicity.
- miRNA Plasmid Composition for CXCR2 Expression Downregulation
Recombinant plasmids boost miRNA production to degrade CXCR2 mRNA, helping restore immune homeostasis when CXCR2 is overexpressed.
- rAAV Production Using Split Adenoviral Rep and Cap Vectors
Separate adenoviral vectors for AAV Rep and Cap raise rAAV yield while improving production stability and scale-up for clinical supply.
- miRNA Expression Composition for CXCR3 Homeostasis Control
Recombinant plasmids boost miRNA against CXCR3 mRNA, lowering overexpression and helping restore immune homeostasis.
- miRNA Plasmid Composition for CXCR2 Expression Suppression
Recombinant plasmids boost miRNA production to degrade or inactivate CXCR2 mRNA, helping restore homeostatic balance in disease.