Fungi TRIZ Cases

Non-condensable media lowers liquid density before mechanical separation, improving separation efficiency while reducing operating costs and emissions.

Removing selected repressor functions helps Trichoderma reesei increase cellulase production and specific enzyme activity.

See how compacted humic acid and microbial granules dissolve completely within minutes while keeping dormant microbes viable for soil applications.

Engineered disulfide bridges help xylanase retain catalytic activity after 80°C treatment for improved industrial heat tolerance.

Engineered α-2,3-sialyltransferases help modified cells produce LST-a with less 3′SL and fewer other HMO byproducts.

Reducing haploinsufficient gene expression drives stable gene amplification in cell factories without costly exogenous selection systems.

Specific HMGR amino acid changes address limited squalene output by enhancing the mevalonate pathway for terpenoid production.

Specific amino acid substitutions improve Candida cylindracea lipase reactivity and residual activity at elevated temperatures for industrial processing.

Different blue-to-red mixing weights in the OLED correction component address viewing-angle color variation while supporting brightness and efficiency.

Steaming grains before inoculation and fermenting them in isolated containers supports mass production while lowering microbial contamination risk.

Modified yeast nucleotide sequences redirect metabolic pathways to raise astaxanthin yield toward industrially competitive levels.

Signal peptides direct target proteins into EVs during microbial secretion, addressing inefficient loading for therapeutic and cosmetic delivery.

Vacuum impregnation loads biochar with nutrients and beneficial microbes, improving viability while reducing leaching and repeat applications.

Uniform stationary phases limit focusing when carrier gas and temperature control are constrained; an outlet-thicker phase improves resolution.

High sugar, cold shock, and organic acids can suppress dough fermentation; AMCC 31195 maintains activity for fermented flour products.

Deleting SEC72 in Pichia pastoris helps release recombinant proteins, reduce intracellular degradation, and maintain cell growth.

Engineered yeast uses XKS and XDH pathways to ferment dextrose into xylitol under mild conditions, reducing erythritol and glycerol by-products.

Segmented fermentation, filtration, rinsing, and inactivation produce scalable mycelial biomass for high-protein food with minimal additives.

Specific CDR-defined antibodies detect COPB2, adding prognostic information beyond PCR for predicting severe COVID-19 symptoms.

This case uses optimized CDR and framework sequences to create long-acting nanobodies that bind and block IL-13.

Straight-chain fatty acids are hydroxylated by engineered CYP450 cells before yeast fermentation produces gamma- and delta-lactones at high yield.

An engineered transcription activator detects wild-type binding sites and triggers growth-limiting gene overexpression to block gene flow without chemicals.

Introducing the RCR1 gene into Brassica increases protein activity and strengthens resistance to Plasmodiophora brassicae.

Combining 2-phenylethanol, ethyl acetate, and diacetyl in a yeast-fermented Solanaceae product broadens flavor beyond 2-phenylethanol alone.

CCR8-selective antibodies remove tumor-infiltrating Tregs through ADCC and ADCP, supporting tumor inhibition while preserving peripheral Tregs.

Microbial production of glycosylation-controlled rOVD helps fortify foods and beverages with soluble, clear, sensory-neutral protein.

Controlled-pH, low-temperature yeast lysis preserves folded proteins that form firm gels when heated for food applications.

Textile layers and spacer elements reinforce a bonded mycelium core to combine structural stability, low weight, and thermal insulation.

Yeast can outcompete mould on conventional media; pectin and agar as sole carbohydrates enable selective growth and accurate CFU counts.

Periodic broth harvesting and fresh-medium addition sustain microorganism cultures, reducing vessel turnaround while maintaining biomass and oil productivity.

Current SIBO breath tests can omit H2S; adding multi-gas measurement improves detection of H2S-positive conditions and guides treatment.

Chemoautotrophic microbes convert hydrogen, carbon dioxide, and oxygen into biomass for high-protein meat-like foods without saturated fats or cholesterol.

Inducible promoter sequences regulate glutamate-triggered expression in Pichia pastoris, improving protein output and simplifying purification.

Electrohydraulic pulses form membrane pores to release proteins and lipids while limiting heating, cell debris, and downstream purification.