Invertebrate Cells TRIZ Cases
- Coral Scaffold Porosity Tuning for Bone Graft Strength Balance
Controlling growth-medium carbonate hardness tunes coral scaffold porosity and strength for bone ingrowth, nutrient flow, and vascularization.
- Baculovirus Vector Stabilization for Multi-Passage rAAV Production
Placing CNE or NAE sequences near the expression cassette keeps baculovirus vectors stable across passages and sustains rAAV yield in insect cells.
- Insect Embryo Cryopreservation Through Waxy Layer Permeabilization
Removing chorion and permeabilizing the waxy layer enables cryoprotectant loading and uniform freezing for viable Black Soldier Fly embryo recovery.
- Sugar-Based Viral Lysis for High-Yield, Low-Aggregation Manufacturing
Sugar-based detergents lyse host cells to release viruses with higher infectivity, lower aggregation, and fewer harmful byproducts.
- Insect Cell Expression Cassette for rAAV VP/Rep Ratio Control
Designed intron splicing in overlapping ORFs controls VP1/VP2/VP3 and Rep78/Rep52 ratios for stable, large-scale rAAV production.