Microorganism Based Processes TRIZ Cases
- Mannanase Variants for Protease-Stable Detergent Enzymes
Targeted deletions and substitutions make mannanase more protease-stable in detergents while preserving activity and cleaning performance.
- Engineered Microorganisms for High-Purity Glycine Fermentation
Metabolic engineering boosts glycine synthesis while suppressing cleavage, enabling lower-impact fermentation with purity suited to food and pharma.
- N-Terminal Truncated Sialyltransferase for Higher 3'-Sialyllactose Yield
Deleting 20-37 N-terminal residues from α2,3-sialyltransferase boosts microbial 3'-sialyllactose production by raising enzyme activity.
- Secreted β-Galactosidase Expression for Low-Impurity GOS Production
By secreting β-galactosidase from Aspergillus oryzae, this case cuts cell debris, simplifies purification, and supports stable GOS production.
- E. Coli PUFA Biosynthesis Using pfaR Feedback Regulation
Overexpressing pfaR with the pEPA Δ1,3,4,9 cluster boosts EPA and other omega-3/omega-6 fatty acids in E. coli for industrial yield.
- Recombinant microorganism expressing fucosyltransferase, and method of producing 2'-fucosyllactose using same
Using BSL-1 recombinant microorganisms instead of H. pylori enables safer, high-yield 2'-fucosyllactose production for food and pharma.
- Halotolerant Microbial Lysis by Osmotic Shock for Biomolecule Recovery
Engineered halotolerant microbes with mechanosensitive channel knockout lyse in distilled water, cutting lysis energy and preserving biomacromolecules.