Conditionally activated MRI contrast agents use reporter-enzyme cleavage to track gene therapy distribution and efficacy non-invasively in real time.
Conditionally activated MRI contrast agents reveal gene therapy biodistribution and enzyme activity in real time, including in the CNS.
Retarder molecules extend tracer T1 in hyperpolarized MRI contrast agents, preserving signal intensity for clearer tissue imaging.
Conventional MRI lacks sensitivity for molecular and metabolic imaging; separate 1H and X-nuclei coils add targeted signal detection.
Controlled meals under 500 kcal let a manganese MRI composition support liver cancer imaging without prolonged fasting.
Crystalline matrices and biological dopants extend T1 relaxation in hyperpolarized MRI probes, helping preserve polarization during clinical imaging.