Organic Compound Preparation TRIZ Cases

A rotating disk pulverizes polyester, using frictional heat to recover dibasic acid and vaporized alkylene glycol.

This composition uses controlled organic halide content to inhibit polymerization during storage while limiting metal corrosion.

Vaporization followed by phase separation uses CO-rich gas to remove heavies, limit catalyst damage, and improve rhodium recovery.

This case uses staged vaporization and phase separation to remove aldehydes and heavies while limiting catalyst degradation and rhodium loss.

Controlled H2 pressure, temperature, and phosphine ligands improve trioxane conversion to omega-hydroxycarboxylic acid esters.

This case uses ring-opening polymerization to produce dual-end fluoropolyethers with controlled molecular weight and dispersion.

A staged synthesis uses controlled reactions and crystallization to produce high-purity KRAS G12C inhibitor intermediates at scale.

A silicone-based additive suppresses foam during continuous methionine crystallization and improves crystal density and flowability.

This case replaces solid reagents with aqueous sodium hypochlorite to improve mixing, selectivity, and safe santalene oxidation scale-up.

This case uses a citric acid slurry to produce high-purity Form 1 despite polymorph mixtures and narrow temperature-pH windows.

This case combines heterogeneous-catalyst oxidation with butyraldehyde extraction and distillation to recover concentrated bio-acetic acid.

CPO and WGS reactors plus CO2 separation tune H2/CO and M ratio for methanol synthesis with heat integration.

Controlled pH, temperature, oxidation, and crystallization improve caronic acid purity and yield while reducing environmental burden.

A telescoped route uses accessible reagents and standard equipment to improve yield and purity while avoiding hazardous conditions.

This continuous esterification process separates azeotropes and recirculates catalyst to improve n-butyl (meth)acrylate yield.

This case uses biodiesel-derived glycerol and chelating groups to reduce inorganic scaling with a lower-carbon synthesis route.

A low boiler column and higher-pressure acetate column remove acetate impurities, recover alcohol, and reduce purification energy.

This case uses alternative activating esters and alkaline coupling to simplify purification and improve semaglutide yield for production.

Pre-impregnating the carrier with alkali controls metal hydrolysis, keeping gold near palladium and improving vinyl acetate selectivity.

This case shows how multifunctional amine structures improve antioxidant stability while reducing gum, sediment, corrosion, and plugging.

Fixed-bed catalysis limits methyl isobutyrate while sustaining methyl methacrylate production.

An anhydrous alkoxy-intermediate route simplifies dione synthesis and improves yield.

This case shows how acid fluoride and cyclic ether polymerization produce difunctional fluoropolyethers while controlling molecular weight.

Replace costly, corrosive oxidants with oxygen-driven Pd-NHC carbonylation for selective oxalate and oxamide production.

Cyclohexane enables lower-temperature water removal during 2-octyl (meth)acrylate esterification.

A staged POSM recovery process separates purge phases, extracts organic compounds with toluene, and purifies mono-propylene glycol.

A soluble germanium chelate keeps PETG/PCTG polymerization homogeneous, reducing reactor-wall deposition and improving viscosity and hue.

Phenol degradation and integrated crystallization remove color impurities from recycled polycarbonate while simplifying BPA purification.

A heated sweep gas maintains permeation-side temperature and lowers humidity to protect the membrane during liquid fuel synthesis.

A base and controlled flow reactor improve Trolox amide oxidative cleavage efficiency while maintaining optical purity.

Alkaline condensation, geraniol alkylation, and high-temperature coupling produce high-purity cannflavin A and C for scale-up.

A metal halide-Lewis base catalyst enables mild acylation of hindered esters with higher yield and selectivity.

This case shows how a synthesized amide carboxylic acid extractant raises yttrium separation while resisting strong acid and base.

This case uses pressurized vaporized glycol to reheat the heating medium, reducing energy input during MEG reclamation.

Formic-acid pretreatment separates lignin and hemicellulose, recycles low-boiling solvent, and prepares cellulose for hydrogenolysis.

Multiple carboxylation reactors convert ethylene oxide with unheated final-reactor inlets and no recycle, reducing energy and capital needs.

Thermotropic liquid-crystalline polyimides enable additive manufacturing below 300°C while improving thermal and solvent resistance.

A continuous copper-based catalyst process converts 1-(4-isobutylphenyl)ethanone to ethanol with high selectivity and simpler purification.

Sequential reactors and solvent crystallization separate BHET from dimers and trimers for high-quality PET recycling.

A staged oxidation, Diels-Alder, reduction, and hydrogenation sequence improves stability and yield for high-energy-density bicyclic fuels.

Lower-alkali hydrolysis improves purity and extraction of the target chlorobicyclic alcohol.

A dividing-wall column combines separations for lower-cost propylene oxide and styrene production.

This case replaces volatile halogenated solvents with a removable solid additive to stabilize photoactive-layer morphology and efficiency.

This process replaces multi-step, transition-metal synthesis with a base-driven reagent route for higher yields and less waste.

This case converts sugar cane bagasse through fermentation and vinyl acetate synthesis into PVA with fewer toxic by-products.

This case uses pulsed microwave heating to produce low-viscosity esters with defined chain lengths for metal-ion complexing.

A staged tray layout with localized catalyst placement improves dialkyl carbonate and diol productivity without enlarging the column.

A specific ligand, Pd catalyst, and Lewis acid convert unsaturated ethers to esters, reducing energy use and by-products.

Heated dissolution and controlled cooling produce filterable sufentanil citrate crystals, reducing manual removal and hazardous milling.

This case addresses catalyst bed fines and flow restrictions using 43–60% nickel alloy granules treated with alkaline solution.