Organic Compounds Purification/Separation/Stabilisation TRIZ Cases
- Systems and methods for separating a mixture of compressed-gas solvents
See how chained recovery stages condense gases at optimized temperatures to separate compressed
- Distillation method for the separation of n-butanal and iso-butanal
See how segmented distillation with optimized temperature and pressure parameters reduces energ
- LDFOP 1,4-Dioxane Solvate for Moisture-Stable Electrolyte Salt Purification
Forming an LDFOP 1,4-dioxane solvate improves crystallinity and filterability while enabling high-purity, moisture-stable electrolyte salt handling.
- Differential Mobility Spectrometry for Enantiomer Separation via Diastereomers
Chiral derivatization converts hard-to-resolve enantiomers into separable diastereomers, enabling sensitive DMS detection and quantification.
- Low-Halide Lanthanum Precursors via Three-Zone Purification
A three-zone sublimation, condensation, and cooling process cuts halides in lanthanum precursors to 10 ppm or less for cleaner vapor deposition.
- FDME Crystallization Purification for Color-Stable Biobased Monomers
Selective solvent crystallization and extraction purify FDME without high-temperature distillation, reducing fouling, color formation, and yield loss.
- Molybdenum-Bismuth Oxide Catalyst Preparation Without Ammonia and NOx
Carbonate-based precursors replace nitric and ammonium salts to curb ammonia and NOx during catalyst preparation while preserving activity.
- Acalabrutinib Synthesis Route for Chiral Purity at Manufacturing Scale
Controlled cyclization, solvent, and catalyst conditions keep acalabrutinib chiral purity high while reducing impurities and batch failures at scale.
- Lamotrigine Hydrate Crystal Form for Stable Oral Liquid Dosing
A lamotrigine monohydrate crystal form enables stable oral suspensions with accurate dosing, improved solubility, and reduced precipitation.
- Carboxylic acid production method
Nanofiltration of fermentation broth before solvent extraction suppresses intermediate phases, speeding separation and improving carboxylic acid purity.
- Hexafluoropropene Composition for Stable High-Purity Transport
Controlled oxygen, HF, or HCl levels suppress hexafluoropropene decomposition during storage and transport while preserving purity.
- Hexafluoropropene Composition Stabilized for Storage and Transport
Controlled oxygen, hydrogen fluoride, or hydrogen chloride levels suppress hexafluoropropene decomposition and preserve purity during storage and transport.
- Hexafluoropropene Composition for Stable Storage and Transport
Controlled oxygen and hydrogen fluoride levels suppress hexafluoropropene decomposition during storage and marine transport, preserving purity.
- Imidacloprid Form I Crystallization with Low Dimer Impurity
Refinement before controlled cooling cuts dimer impurity below 0.5%, enabling selective crystallization of stable imidacloprid Form I.
- Cyclodextrin Encapsulation of Bicycloalkanes for Higher Inclusion Yield
A water-organic mixed solvent with light shielding improves bicycloalkane cyclodextrin inclusion yield, purity, and scale-up efficiency.
- THR Beta Agonist Intermediate Synthesis Without Chiral Separation
A palladium-catalyzed route builds the THR beta agonist intermediate with high yield, controllable quality, and no SFC chiral separation.
- Organic Compound Purification by UV Lead Conversion and Removal
UV irradiation changes lead impurities in organic compounds into removable forms, enabling sub-ppb purification with fewer side reactions.
- Lanraplenib Sesquisuccinate Crystallization for Free Base Exclusion
Controlled THF crystallization and acid ratio tuning suppress free base impurities in lanraplenib sesquisuccinate for stable, high-purity formulations.