Oxidoreductases TRIZ Cases
- Engineered Yeast Hernandulcin Biosynthesis Using NtEAH Oxidation
Engineered yeast uses NtEAH, bisabolol synthase, and P450 reductase to raise hernandulcin yield and purity for scalable production.
- Novel promoter and l-amino acid production method using same
A T-to-G change in the lactate dehydrogenase promoter cuts lactic acid while boosting L-glutamic acid production in Corynebacterium.
- Recombinant miRNA Plasmid Composition for Target Biomolecule Suppression
Engineered plasmids raise miRNA levels in target cells to degrade or inactivate mRNA, lowering harmful biomolecule expression and restoring homeostasis.
- Mutated Carbonyl Reductase for Thermostable Chiral Synthesis
Specific amino acid substitutions improve carbonyl reductase thermal stability and stereoselectivity, cutting enzyme use in chiral compound production.
- KAH Enzyme Variants for High-Yield Steviol Glycoside Biosynthesis
Variant KAH enzymes improve kaurenoic acid to steviol conversion in yeast, enabling higher-yield production of Reb M and related steviol glycosides.
- Saponarioside Biosynthetic Enzymes for Quillaic Acid Pathway Engineering
Mapped oxidation and glycosylation enzymes reconstruct the quillaic acid pathway, enabling scalable triterpenoid saponin production in host cells.
- Immobilized Enzyme Reactor Cells for Controlled Formate Bioelectrocatalysis
A surface-linker-enzyme reactor cell enables controlled electron transfer, simplifying formate or formic acid production.
- Engineered Ketoreductase Variants for Stable R-3-Hydroxythiolane Synthesis
Targeted ketoreductase mutations improve stereoselective 3-ketothiolane reduction while maintaining activity, thermostability, and solvent stability.
- Immobilized Enzyme Reactor Cells for Direct H2O2 Electron Transfer
Direct enzyme-to-electrode linking simplifies bioelectrocatalysis and improves control of hydrogen peroxide production.
- Plasma-Assisted Enzymatic Reaction with Protected Enzyme Activity
A one-pot plasma biocatalysis setup uses porous enzyme immobilization to preserve activity while boosting reactive species and yield.
- Flavanone 2-Hydroxylase Gene for Blue Flower Pigment Pathways
An ODD-family enzyme hydroxylates flavanones at the 2-position, supporting 2-hydroxyflavanone production and blue-flower modification.
- UGT76G1 Variant Enzymes for Efficient Reb M Bioconversion
Variant UGT76G1 enzymes improve Reb D-to-Reb M conversion in engineered yeast, addressing low wild-type efficiency and productivity.
- HRP Polypeptide Mutations for Soluble E. coli Expression
P146 and N275 substitutions target low soluble yield and instability in recombinant HRP production in E. coli.