Recombinant DNA-Technology TRIZ Cases
- Environmental Memory Seeds with DNA Methylation for Stress Tolerance
This case uses stress-conditioned seeds and promoter methylation to improve yield, maturity, and inherited crop stress tolerance.
- Nucleosidase Treatment for Nucleic Acid Seasoning Taste
Nucleosidase treatment converts ribonucleotides into purine bases, overcoming raw material constraints to boost GMP and IMP content in seasonings.
- Humanized IL-7 Rodents With Endogenous Regulatory Control
Replacing endogenous exons with human coding sequences at the native locus prevents immune abnormalities while preserving normal T cell populations.
- Alpha-amylase variants for cold-water detergent stability
Specific amino acid modifications enable alpha-amylase variants to maintain wash performance and stability against chelating agents and surfactants.
- Engineered MBD Variants for oxi-mC Configuration Resolution
Segmented affinity enrichment with engineered binders resolves binary read-out limitations to map genome-wide oxidation states.
- IgG4 Antibody HCP Binding Reduction via Fc Region Modification
Targeted amino acid substitutions in the IgG4 hinge region reduce host cell protein binding, simplifying purification and lowering manufacturing costs.
- Agrobacterium Maize Transformation Without Selection Step
Removing the intermediate selection step from Agrobacterium-mediated maize transformation reduces mutation rates while maintaining high efficiency.