Samples Introduction/Extraction TRIZ Cases

Broadens ion clouds via differential velocity reduction to extend transient detection windows.

Dynamic vacuum pump speed control manages gas flow during transfer tube swaps, extending pump lifespan while maintaining stable chamber pressure.

A mass spectrometry device uses ultrasonic vibration to convert samples into fine liquid particles for plasma ionization.

Dynamic thermal desorption separates mixture components by boiling point to reduce spectral peak congestion and improve detection accuracy.

Dissolving a water-soluble pellet cup after pressing eliminates thickness variation in water-insoluble MALDI samples.

Image-guided tissue sampler acquires samples from regions of interest, reducing data collection time compared to scanning entire specimens.

Electrospray deposition modifies surfaces with proteins under atmospheric pressure, eliminating vacuum requirements and nonspecific bonding.

A sputter neutral particle mass spectrometer uses a profiler and driving system mirror to control laser condensing spot position.

A MALDI ion source merges laser and imaging optical paths through shared elements to direct radiation onto target areas.

A nanospray emitter assembly integrates a solid phase extraction cartridge for efficient sample loading and analysis.

Segmented curved probe minimizes aerosol dispersion and washout time, enabling high spatial resolution and sample throughput.

GCIB processing system uses molecular beams to optimize localized pressure for controlled substrate etching.

A continuously moving eccentric target reduces spray divergence and improves ionization efficiency across diverse analyte polarities.

Storing individual mass spectra in a multidimensional data field enables computational algorithms to eliminate noise and improve measurement precision.

Electrically conductive filtration substrates separate biological samples while enabling direct mass spectrometry ionization.

Mass spectrometry system uses collision-induced dissociation to fragment analyte ions for structural analysis.

An integrated ion separation spectrometer replaces radioactive sources with a micro-corona ionizer to eliminate safety risks and reduce device complexity.

A non-radioactive plasma ion source uses planar electrodes to generate a homogeneous electric field that directs ionized particles toward an analyte outlet.

Calcium salt complexation prevents proton stripping during differential mobility spectrometry, enabling accurate cyclic peptide quantitation.

Segmented non-metallic capillaries prevent turbulence and ion losses while enabling electrical potential application.

A Laval nozzle directs ions via a supersonic gas jet, reducing losses below 10 percent and boosting mass spectrometer sensitivity.

Segmenting the mass spectrometer into a stationary analyzer and mobile probe resolves bulk constraints while minimizing ion loss.

Reagents convert non-volatile compounds into volatile forms, enabling detection by thermal desorption mass spectrometry.

Integrated solvent delivery system eliminates external gas cylinders, enabling precise on-site analysis with minimal sample preparation.

A channel-free rotor and stator interface transfers analytes via carrier gas to an analyzer.

Integrating ESI, APCI, and LDTD into one interface reduces wiring complexity and cross-contamination while maintaining independent method optimization.

Low thermal mass drift tube enables rapid temperature ramping to prevent thermal decomposition of labile explosives during detection.

Segmented sampling chambers and curved collectors reduce particle adherence to walls, enabling compact device size and improved collection efficiency.

A laser microdissection apparatus positions a thermofusible film below the sample for bottom irradiation and direct reagent application.

Gas phase introduction eliminates dilution and contamination, achieving attomole detection limits in mass spectrometers.

Ion mobility spectroscopy pre-screens samples before mass spectrometry analysis, reducing ion trap contamination and improving throughput.

APME-FID technique eliminates solvent reagents and reduces device complexity while enabling efficient mass spectrometry of diverse samples.

Silicate minerals store standard gas for on-orbit mass spectrometer calibration, eliminating heavy gas cylinders and leakage risks.

A laser sensor monitors the gap between a sample collection instrument and the analysis surface to maintain optimal spacing.

Stacked microengineered chips create an einzel lens that focuses ions and separates neutrals, reducing alignment complexity and cost.

Mass spectrometry replaces slow histology to detect 2-HG biomarkers, resolving delayed diagnostic feedback that limits immediate surgical decision-making.

Frame body markers on a sample support enable camera recognition of the ionization region position.

Helical resistive drift tube structures guide ion movement through constant electric fields in portable chemical detection systems.

A universal sample introduction system processes liquid and gaseous samples using a gas-permeable membrane interface.

A probe forms a liquid bridge on an oscillating substrate to generate ions under atmospheric pressure.

A cell sample preparation method merges imaging and mass cytometry workflows using elemental tags to enable direct cellular data correlation.

An intermediate ion store enables forward and backward ion travel along a longitudinal axis for off-axis ejection to a mass analyzer.

Laminar carrier gas flow transports sample molecules through a small inlet, resolving the contradiction between vacuum maintenance and sampling efficiency.

A real-time calibration device injects trace calibration agent molecules into the sample injection pipeline of an ion mobility spectrometer.

Real-time droplet monitoring adjusts heated gas flow and temperature to prevent impurity contamination and maintain ionization sensitivity.

A gas analyzer alternates sample and comparative gas flows to isolate adsorbed substance interference during microparticle composition measurement.

Segmented ion mobility separation and mass spectrometry eliminate vacuum integration complexity while enabling precise spatial focusing of deposited ions.

Metal oxide surfaces replace organic matrices to eliminate background interference, enabling precise detection of small molecules in complex mixtures.

Computer-controlled regulation adjusts carrier gas flow through multiple capillaries for precise concentration delivery.