Steroids TRIZ Cases
- 6,7-alpha-epoxidation of steroid 4,6-dienes using methyltrioxorhenium
Replacing animal-derived cholic acid with plant sterols eliminates supply constraints and contamination risks while enabling scalable production.
- Amphipathic PEG-Cholesterol Compounds for Quantitative Cell Immobilization
Amphipathic compounds with hydrophobic domains and PEG moieties anchor into cell membranes to provide quantitative immobilization.
- Drospirenone Synthesis via Palladium-Catalyzed Oxidation
A palladium(II) catalytic system converts steroid precursors into drospirenone using gaseous oxygen.
- Phytosterol Synthesis of Cholesterol and Vitamin D3
A multi-step synthetic process converts crude phytosterols into vegan cholesterol and vitamin D3 using tosylating, Grignard reactions, and irradiation.