Sulfonylurea Active Ingredients TRIZ Cases
- Relacorilant Co-Administration Without CYP2C9 Dose Reduction
Clinical data showed relacorilant can be co-administered with CYP2C9 substrates without dose reduction or the expected rise in plasma exposure.
- SUR1-TRPM4 Inhibitor Use During Thrombectomy for Stroke Edema
Blocking SUR1-TRPM4 during mechanical thrombectomy helps limit cerebral edema and neurological decline in large ischemic stroke lesions.