Unknown Materials TRIZ Cases
- Oncolytic Virus Expressing Soluble CD44 for Glioblastoma Treatment
Engineered oncolytic herpes simplex virus secretes soluble CD44 to disrupt tumor microenvironment signaling and enhance immune cell infiltration.
- Methazolamide Carbonic Anhydrase Inhibition Pancreatic Cancer
Methazolamide treats pancreatic cancer by blocking carbonic anhydrase to reduce recurrence rates.
- Bifidobacterium breve Nutritional Composition for Infant Asthma Prevention
Infant nutritional composition with Bifidobacterium breve addresses limited long-term probiotic efficacy by establishing early immune tolerance.
- Epicardial SVF Construct for Myocardial Infarction Treatment
An epicardial stromal vascular fraction construct retains regenerative cells on the heart surface to promote coronary neovascularization.
- Placental Stromal Cells Inhibit Tumor Growth and Metastasis
Activated placental adherent stromal cells halt tumor expansion and metastasis without requiring long-term host survival.
- Oncolytic Adenovirus and Checkpoint Inhibitor Combination Therapy
Combining oncolytic adenovirus with checkpoint inhibitors overcomes treatment resistance while reducing systemic side effects.
- Microfluidic Alginate Microparticles for Size and Shape Control
Microfluidic droplet formation controls alginate gelation to create monodisperse microparticles under 50 μm with defined shapes.
- Coix Seed Oil Triglyceride Composition for Tumor Treatment
Isolating eight specific triglycerides from Coix seed oil resolves quality control challenges while enabling safe tumor treatment and immunoenhancement.
- Ginsenoside Rg2 Autophagy Induction iPSC Endothelial Cell Senescence
Rg2 treatment promotes mTOR-independent ULK1-mediated autophagy to overcome premature senescence and maintain endothelial cell phenotype maturity.
- Myoblast Injection for Anal Sphincter Repair
Injecting autologous myoblasts into the external anal sphincter repairs deficient tissue to improve long-term continence without surgical morbidity.
- Natural Antibiotic Supplement Formulation for Immune Support
A natural health supplement combining garlic, onion, and vinegar to support the immune system.
- Bone Marrow Stem Cell Therapy for Limb Ischemia Microenvironment
Modified microenvironments with antioxidants enhance bone marrow cell efficacy against aging-related ischemia, resolving reduced regenerative activity.
- Alcohol-Soluble Broth Extract for Gastrointestinal Barrier Repair
Ethanol extraction isolates active agents from animal broth to strengthen epithelial cell layers and improve intestinal barrier function.