Vector-Based Foreign Material Introduction TRIZ Cases

Recombinant plasmids raise miRNA levels to silence serotonin receptor mRNA, helping restore homeostatic control when receptor expression is dysregulated.

Gene editing links a distal endogenous promoter to fertility-restorer genes, boosting plant expression without heterologous DNA insertion.

Recombinant plasmid and viral vector delivery boost miRNA expression to degrade target mRNA and suppress complement or factor production.

Recombinant plasmids boost miRNA production to degrade coagulation factor mRNA, lowering thrombotic risk while preserving hemostatic balance.

By boosting endogenous miRNA, recombinant plasmids degrade serotonin receptor mRNA to reduce overexpression and restore homeostatic balance.

Upregulated miRNA expression degrades target mRNA to suppress complement and factor production and restore homeostatic balance.

Engineered plasmids boost miRNA expression to degrade checkpoint-target mRNA and lower PD-1, PD-L1, CTLA4, or IDO1 bioavailability.

A recombinant plasmid boosts miRNA production to degrade androgen receptor mRNA and reduce harmful over-expression.

Recombinant plasmids boost miRNA that binds serotonin receptor mRNA, lowering receptor bioavailability to counter dysregulation.

A dominant resistance gene helps breeders control Cercospora leaf spot in beets while reducing fungicide use, crop loss, and yield penalties.

Target-cell plasmids upregulate miRNA that degrades cytokine mRNA, reducing inflammatory biomolecule bioavailability and restoring homeostasis.

Modified rab17 promoter constructs and BBM genes enable mature-tissue plant transformation while preventing premature transgene excision.

Recombinant plasmids drive miRNA expression to degrade cytokine mRNA, lowering cytokine bioavailability and helping restore homeostasis.

Reducing Pub21 and Pub17 susceptibility gene activity helps tomato plants resist lesion-forming pathogens while simplifying breeding beyond small-effect QTLs.

Partially complementary 5' and 3' UTRs raise protein expression while limiting translation-initiation interference from secondary structures.

Shorter female corn plants and optimized male-female row ratios improve pollen flow, fertilization, and hybrid seed yield.

NEENA sequences linked to plant promoters raise RNA stability and synthesis, reducing unpredictable transgene expression and screening effort.

Boosting CHK2, CHK3, or CHK4 expression makes plant cells more responsive to cytokinins, improving shoot, root, and whole-plant regeneration.

Recombinant plasmids raise miRNA levels to degrade target mRNA and reduce complement or factor bioavailability when existing regulation is inadequate.

Recombinant plasmids boost miRNA expression to degrade target mRNA and lower complement or factor bioavailability when existing regulation is inadequate.

New K. marxianus promoters and terminators enable constitutive high protein expression across carbon sources and high-temperature growth.

A recombinant plasmid boosts miRNA production to degrade CXCR1 mRNA, helping restore homeostasis when CXCR1 is dysregulated.

A recombinant plasmid and AAV delivery approach boosts miRNA production to degrade CXCR1 mRNA and restore immune homeostatic balance.

Plasmid-expressed miRNA targets checkpoint mRNA for degradation or inactivation, reducing PD-1 and PD-L1 bioavailability while restoring homeostasis.

Glycine-derived promoters and terminators expand soybean expression cassette options for robust constitutive protein production across multiple tissues.

Low-homology synthetic snRNA promoters prevent U6-driven plasmid recombination and support stable multiplex gRNA expression in plant CRISPR.

Novel stress-induced terminators and MARs boost recombinant protein output in plant expression vectors, raising yield up to 10-fold.

Replacing Triton X-100 with Tween 20 or sodium deoxycholate enables virus extraction with lower residual host DNA after nuclease treatment.

A segmented promoter sequence boosts gene expression across Corynebacterium, Escherichia, and Bacillus to raise amino acid production.

Recombinant plasmids raise miRNA levels to degrade serotonin receptor mRNA, reducing receptor bioavailability and restoring homeostatic balance.