Automated Beam Alignment in Biomedical Illumination Devices

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Solution Overview

Problem

Biomedical devices such as flow cytometers and gene sequencers require precise illumination for microfluidic components, but existing optical subsystems lack efficient automated beam steering and alignment, leading to instability and the need for frequent manual recalibrations.

Innovation Solution

A biomedical illumination device with an integrated beam shaping element and an automated beam steering system, featuring actuator-controlled mirrors and a control device that continuously monitors and adjusts the beam geometry, enabling automatic alignment and recalibration without manual intervention.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If manual beam alignment and recalibration are used, then the device can be operated with simpler components, but the device requires frequent manual intervention and has lower operational stability

Engineering Contradiction:
Improveoperational stabilityVSAvoidmanual intervention requirement
Core Design Contradiction:
ReliabilityVSEase of operation

Solution Approach 1:

The system performs self-alignment and self-calibration through automated feedback control. The control device continuously monitors beam positions and automatically adjusts mirror actuators to maintain optimal beam alignment, enabling the system to service itself without external manual intervention and thereby improving operational reliability

Inventive Principle:
Principle #25Self-service

Solution Approach 2:

The system implements continuous feedback control by monitoring beam positions at the target and automatically adjusting mirror actuators based on detected deviations. This closed-loop feedback mechanism maintains stable beam alignment over time, resolving the contradiction between operational reliability and manual intervention requirements

Inventive Principle:
Principle #23Feedback

2Measurement precision

If automated beam steering system is implemented, then beam alignment precision is improved, but device complexity increases

Engineering Contradiction:
Improvebeam alignment precisionVSAvoidsystem complexity
Core Design Contradiction:
Measurement precisionVSDevice complexity

Solution Approach 1:

The system replaces manual mechanical alignment procedures with automated electro-mechanical mirror actuators controlled by electronic feedback loops. This substitution of manual mechanical operations with automated electro-mechanical systems improves beam alignment precision while the modular architecture manages the resulting complexity

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The mirror actuators serve multiple functions: they perform both beam steering and beam alignment tasks, and the same control device handles both monitoring and adjustment functions. This multi-functionality reduces the need for separate dedicated components, thereby managing device complexity while achieving high precision

Inventive Principle:
Principle #6Universality (Multi-functionality)

3Productivity

If frequent manual recalibration is required, then the device can have simpler automation systems, but productivity is reduced due to downtime

Engineering Contradiction:
Improveoperational uptimeVSAvoidautomation level
Core Design Contradiction:
ProductivityVSExtent of automation

Solution Approach 1:

The automated beam steering system maintains continuous beam alignment without interruption to the main operation. The feedback control operates continuously in the background, ensuring that beam alignment is maintained without requiring downtime for recalibration, thereby maximizing productivity while implementing high-level automation

Inventive Principle:
Principle #20Continuity of useful action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The solution provides stable and precise illumination for biomedical applications by automating beam alignment and recalibration, reducing the need for manual intervention, increasing operational lifespan, and ensuring consistent performance over time.

Implementation Method 1

one or more of the beams are directed towards one or more actuator-controlled mirrors; the one or more actuator-controlled mirrors configured to steer the one or more beams

Methodology Applied
Scientific EffectReflection: Reflection

Implementation Method 2

the beam shaping component comprises a diffractive optical element, DOE

Methodology Applied
Scientific EffectDiffraction: Diffraction

Implementation Method 3

the beam shaping component comprises a diffractive optical element, DOE or a refractive optical element, ROE

Methodology Applied
Scientific EffectRefraction: Refraction

Data Source

PatentUS20250164769A1Multi-wavelength laser beam pattern generator with automated beam alignment
Publication Date: 2025.05.22 MODULIGHT CORP
  • US20250164769A1 patent drawing
  • US20250164769A1 patent drawing
  • US20250164769A1 patent drawing

AI summary

Example embodiments provide a biomedical illumination device enabling multiwavelength laser line generation with automated beam alignment. The biomedical illumination device may include a plurality of laser light sources configured to provide beams of one or more wavelengths, wherein one or more of the beams are directed towards one or more actuator-controlled mirrors; the one or more actuator-controlled mirrors configured to steer the one or more beams for passing through a beam shaping element, wherein for each of the one or more beams at least one actuator-controlled mirror is configured for steering the respective beam automatically according to instructions received from a control device; the beam shaping element configured to output a beam pattern having a certain geometry for illumination of a microscopic sample based on the steered beams; and the control device configured to monitor the beams output from the beam shaping element to determine a position of the output beam pattern in relation to a target beam pattern position at the sample; determine instructions for one or more of the actuator-controlled mirrors to tilt in at least one axis based on a difference between the monitored position of the output beam pattern and the target beam pattern position at the microscopic sample; and transmit the instructions to the one or more actuator-controlled mirrors.