Carob Silicate Mycotoxin Binding Composition

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Solution Overview

Problem

Current methods for addressing mycotoxin contamination in animal feeds, such as dilution, physical separation, and detoxification, are labor-intensive and often ineffective against a broad range of mycotoxins, with existing binders like mineral clays and yeast cell wall extracts showing limited efficacy in binding toxins beyond aflatoxins.

Innovation Solution

A composition comprising carob, a silicate mineral, and vegetable-origin glucans as immune stimulants, which significantly enhances the binding efficiency of a broader range of mycotoxins including zearalenone and T2 toxin, with a preferred ratio of 55-65% bentonite, 15-25% carob, and 5-15% glucans, effectively binding at least three mycotoxins commonly found in animal feeds.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If mineral clays (bentonite, montmorillonite) are used as mycotoxin binders, then aflatoxin binding is effective, but binding efficacy for other mycotoxins (zearalenone, T2 toxin) is limited

Engineering Contradiction:
Improvebinding efficacyVSAvoidrange of mycotoxins bound
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent combines carob powder (10-30% w/w) with silicate mineral (40-80% w/w) to create a composite binder that leverages the adsorption capacity of both materials. Carob contains tannins and polyphenols that bind mycotoxins through multiple mechanisms, while the silicate mineral provides additional adsorption sites, together achieving broad-spectrum binding of aflatoxins, zearalenone, T2 toxin, and other mycotoxins

Inventive Principle:
Principle #40Composite materials

Solution Approach 2:

The patent modifies the chemical properties of the binder by incorporating carob, which changes the binding mechanism from purely physical adsorption (mineral clay) to include chemical interactions such as hydrogen bonding, hydrophobic interactions, and complexation with tannins. This parameter change enables effective binding of diverse mycotoxin structures

Inventive Principle:
Principle #35Parameter changes

2Object-affected harmful factors

If dilution of contaminated feeds is used, then mycotoxin concentration is reduced, but labor intensity increases and effectiveness is limited

Engineering Contradiction:
Improvemycotoxin concentrationVSAvoidlabor efficiency
Core Design Contradiction:
Object-affected harmful factorsVSProductivity

Solution Approach 1:

The patent introduces a mycotoxin-binding composition as an intermediary substance that chemically interacts with mycotoxins in the feed. This composition acts as a mediator that captures and inactivates mycotoxins through adsorption and chemical binding, eliminating the need for manual dilution or separation operations while effectively reducing mycotoxin availability to animals

Inventive Principle:
Principle #24Intermediary (Mediator)

3Object-affected harmful factors

If physical separation to remove highly contaminated feeds is used, then mycotoxin exposure is reduced, but labor intensity and complexity increase

Engineering Contradiction:
Improvemycotoxin exposureVSAvoidseparation process complexity
Core Design Contradiction:
Object-affected harmful factorsVSDevice complexity

Solution Approach 1:

Instead of using complex physical separation equipment and procedures, the patent employs a simple mycotoxin-binding composition that can be uniformly mixed into the feed. This intermediary substance selectively binds mycotoxins throughout the feed matrix, achieving effective removal without requiring sophisticated separation devices or complex operational procedures

Inventive Principle:
Principle #24Intermediary (Mediator)

4Object-affected harmful factors

If ammoniation or heating is used to detoxify feeds, then mycotoxin levels are reduced, but energy consumption increases and effectiveness against certain mycotoxins is limited

Engineering Contradiction:
Improvemycotoxin levelsVSAvoidenergy consumption
Core Design Contradiction:
Object-affected harmful factorsVSUse of energy by moving object

Solution Approach 1:

The patent replaces energy-intensive thermal or chemical detoxification processes with a chemical binding approach using carob and silicate mineral. The binding composition chemically interacts with mycotoxins at ambient conditions through adsorption and complexation, eliminating the need for high-temperature heating or ammoniation while achieving comparable or superior detoxification effectiveness across multiple mycotoxin types

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The composition demonstrates a remarkable increase in binding efficiency for zearalenone and T2 toxin, outperforming comparative compositions, with nearly complete binding of zearalenone and substantial binding of T2 toxin, thereby improving animal health and feed nutritional quality.

Implementation Method 1

A composition for binding and thereby inactivating mycotoxin in an animal feed... comprising carob, a silicate mineral... The composition demonstrates a remarkable increase in binding efficiency for zearalenone and T2 toxin

Methodology Applied
Scientific EffectAdsorption: Adsorption

Implementation Method 2

A composition for binding and thereby inactivating mycotoxin in an animal feed comprises carob, a silicate mineral... binding efficiency for zearalenone and T2 toxin, outperforming comparative compositions

Methodology Applied
Scientific EffectAdsorption: Adsorption

Data Source

PatentEP2587935B1Mycotoxin binding compositions
Publication Date: 2016.04.06 PERSTORP AB
  • EP2587935B1 patent drawing

AI summary

The present application refers to a composition for binding and thereby inactivating mycotoxin, the composition comprising from 10 to 30 % by weight of carob, 40 to 80 % by weight of a silicate mineral and 1 to 25 % by weight of an immune stimulant.