Capillary Electrophoresis Polymer Storage Using Vacuum-Sealed Bag

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Solution Overview

Problem

In capillary electrophoresis apparatus, the polymer used as a separation medium deteriorates due to exposure to air, leading to inefficient use as the surface polymer remains unused until the end, causing denaturation and oxidation.

Innovation Solution

A polymer container that seals the polymer from air contact, using a flexible plastic bag or pouch with a vacuum-sealed design and a cap system to prevent oxidation, ensuring the polymer is used efficiently by eliminating air exposure.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Loss of substance

If the polymer is stored in a polymer bottle with the tube extending to the bottom, then the polymer at the bottom is used first, but the polymer at the surface remains until the end and deteriorates due to air exposure

Engineering Contradiction:
Improvepolymer deteriorationVSAvoidpolymer utilization efficiency
Core Design Contradiction:
Loss of substanceVSProductivity

Solution Approach 1:

The polymer is stored in a polymer bag that is vacuum-sealed to create an inert environment free from air contact. This prevents oxidation and deterioration of the polymer, allowing complete utilization of the polymer without waste while maintaining its effectiveness throughout the entire storage period

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

Solution Approach 2:

A flexible polymer bag is used instead of a rigid polymer bottle. The bag can be collapsed as polymer is dispensed, ensuring that air cannot enter and contact the polymer surface. This flexible containment structure enables complete polymer utilization while preventing deterioration

Inventive Principle:
Principle #30Flexible shells and thin films

2Ease of operation

If the polymer surface is exposed to air in the polymer bottle, then the polymer can be easily accessed, but the polymer deteriorates due to oxidation and denaturation

Engineering Contradiction:
Improvepolymer accessibilityVSAvoidpolymer stability
Core Design Contradiction:
Ease of operationVSReliability

Solution Approach 1:

The polymer is stored in a vacuum-sealed polymer bag that creates an inert environment, preventing air contact and oxidation. The polymer remains stable and reliable while still being easily accessible through the pump system that draws polymer from the bag

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

3Productivity

If the polymer is used until the end in the polymer bottle, then complete polymer utilization is achieved, but the remaining polymer is denatured and wasted

Engineering Contradiction:
Improvepolymer utilization efficiencyVSAvoidpolymer waste
Core Design Contradiction:
ProductivityVSLoss of substance

Solution Approach 1:

The vacuum-sealed polymer bag creates an inert environment that prevents polymer deterioration throughout the entire usage period. This enables complete polymer utilization without waste, as the polymer remains effective until the very end of the container

Inventive Principle:
Principle #39Inert atmosphere (Inert environment)

Solution Approach 2:

The invention prevents polymer waste by maintaining polymer integrity throughout storage and usage. The pump system is designed to extract polymer efficiently until the bag is completely empty, ensuring no usable polymer is discarded due to deterioration

Inventive Principle:
Principle #34Discarding and recovering

Data Source

PatentUS8454812B2Capillary electrophoresis apparatus
Publication Date: 2013.06.04 HITACHI HIGH TECH CORP
  • US8454812B2 patent drawing
  • US8454812B2 patent drawing
  • US8454812B2 patent drawing

AI summary

A capillary electrophoresis apparatus capable of efficiently using a polymer in a polymer container is provided. The present invention relates to a mechanism for efficiently using the polymer in the polymer container in a capillary electrophoresis apparatus for the electrophoresis with a separation medium filled in a capillary. According to the present invention, since the polymer in the polymer container is not contacted with the air, deterioration of the polymer by oxidation can be prevented.