Core Biopsy Needle With Tissue-Adhesive Surface for Complete Sampling
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Solution Overview
Problem
Existing core biopsy needles with diameters larger than 1 mm cause significant side effects and require complex procedures due to their size, often resulting in incomplete tissue samples that are inadequate for histological analysis.
Innovation Solution
A core biopsy needle with a reduced outer diameter, utilizing a tissue-holding surface on the inner needle that adheres to the tissue via chemisorption, physisorption, and friction, ensuring complete tissue samples are obtained without fragmentation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Manufacturing precision
If core biopsy needles with large outer diameter (>1mm) are used, then complete tissue samples can be obtained, but side effects such as bruising, hematoma, swelling, pain, and altered appearance occur
Solution Approach 1:
The invention changes the critical parameter of needle outer diameter from conventional >1mm to <1mm (specifically 0.5-0.8mm), enabling complete tissue sample acquisition with minimal side effects. This parameter change is achieved through specialized needle geometry and tissue adhesion mechanisms that compensate for the smaller size.
Solution Approach 2:
The inner needle features a specialized tissue-adhesive surface with specific chemical properties (charged groups, hydrophilic/hydrophobic balance) that create strong local adhesion to tissue. This localized quality enhancement at the tissue-contact surface allows effective tissue capture despite the reduced overall needle diameter.
2Manufacturing precision
If core biopsy needles with large outer diameter (>1mm) are used, then complete tissue samples can be obtained, but the procedure requires local anesthesia and surgical incision
Solution Approach 1:
Reducing the needle outer diameter to <1mm eliminates the need for surgical incision and local anesthesia, simplifying the procedure. The small diameter allows percutaneous insertion without cutting, while the tissue-adhesive surface ensures complete sample acquisition is maintained.
Solution Approach 2:
The invention extracts and eliminates the need for auxiliary procedures (local anesthesia, surgical incision) by using a needle design that achieves complete tissue sampling through minimal percutaneous insertion. Only local disinfection remains necessary.
3Object-affected harmful factors
If smaller needle diameter is used, then side effects are reduced, but smaller tissue pieces are obtained which are inadequate for histological analysis
Solution Approach 1:
The invention optimizes the needle outer diameter to 0.5-0.8mm, a range small enough to minimize side effects but large enough to accommodate complete tissue cores. This parameter optimization is complemented by the tissue-adhesive surface that ensures complete tissue capture.
Solution Approach 2:
The inner needle's tissue-adhesive surface with specific chemical properties (charged groups, hydrophilic/hydrophobic balance) creates strong localized adhesion that ensures complete tissue capture. This localized quality enhancement compensates for the reduced needle diameter, maintaining tissue sample adequacy for histological analysis.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The needle allows for efficient, minimally invasive biopsy procedures with reduced side effects and complete tissue samples suitable for histological analysis, eliminating the need for local anesthesia and surgical incisions.
Implementation Method 1
the tissue-holding surface is adapted such that a tissue adheres to the at least one tissue-holding surface, particularly by chemisorption and/or physisorption and/or friction
Implementation Method 2
the tissue-holding surface is adapted such that a tissue adheres to the at least one tissue-holding surface, particularly by chemisorption and/or physisorption and/or friction
Implementation Method 3
the tissue-holding surface is adapted such that a tissue adheres to the at least one tissue-holding surface, particularly by chemisorption and/or physisorption and/or friction
Data Source
AI summary
The invention relates to a core biopsy needle (1) for obtaining a tissue sample comprising a hollow outer needle (10) extending along a longitudinal axis (L), and an inner needle (20), which is at least partially arranged or arrangeable within said outer needle along said longitudinal axis (L), wherein said inner needle (20) comprises at least one tissue-holding surface (21), wherein said tissue-holding surface (21) is adapted such that a tissue (3) adheres to the at least one tissue-holding surface (21), when the core biopsy needle (1) is inserted into the tissue (3).