Surgical Adhesives TRIZ Cases

A stabilized biodegradable cyanoacrylate forms a flexible occluding polymer, then degrades to drive tissue ingrowth and lasting conduit closure.

A zein-catechol adhesive enables fast, biocompatible tissue sealing in biofluids, avoiding the toxicity and synthesis complexity of existing sealants.

β-TCP-binding peptides tether BMP-2 on electrospun bone fibers, limiting leakage and supporting sustained regeneration at defect sites.

A foam substrate with high elongation and a compliant acrylic adhesive helps skin patches stay attached while reducing irritation, peeling, and pain.

Reactive surgical compositions cure from a moldable state to a hardened form, reducing brittleness while supporting bone hemostasis and reconstruction.

Premixed radiopaque cyanoacrylate stays shelf-stable and sterilizable while remaining visible during and after in situ curing.

An alginate coating gelled with divalent ions secures transplanted tissue on organ surfaces while supporting long-term engraftment and proliferation.

A sprayable PLCL fiber blend uses controlled hydrolytic erosion and viscoelasticity to prevent adhesions while supporting wound healing.

An oCMC-mMC adhesive hydrogel forms a rapid in situ gel with strong tissue bonding, low cytotoxicity, and enzymatic resistance.

Platelet-shaped crosslinked gelatin particles improve fine-vessel packing, temporary occlusion, and controlled recanalization with fewer off-target effects.

A polymer-calcium phosphate injectable adhesive replaces metal fixation in comminuted fractures while improving bone adhesion, strength, and healing.

A flexible synthetic matrix with PEG-NHS and PEG-NH2 forms an adhesive gel barrier that seals bleeding, fluid leaks, and air leaks on moving tissue.

Prewetted gelatin and thrombin form a flowable cross-linkable sealant that closes lung tracts quickly and helps reduce pneumothorax risk.

Room-temperature α-zein gel balances bioink printability, biocompatibility, and mechanical strength for porous 3D tissue and hemostatic materials.

Frangible capsules keep adhesive components separate until energy-triggered release at the heart valve, avoiding premature setting during treatment.

Directly reconstituting dry thrombin in a biocompatible paste cuts syringe handling and enables fast, uniform haemostat preparation.

A tissue-adhesive inner needle captures complete biopsy cores with a sub-1 mm outer diameter, reducing pain, bruising, and procedure complexity.

A branched PCL-PEG bioadhesive balances strong tissue adhesion with low inflammation and easy body-temperature application.

A calcium phosphate bone substitute turns clay-like for hand shaping, then hardens within 30 minutes to simplify defect filling without injectors.

Encapsulating drug reservoirs before gentle hydrogel gelation keeps particles evenly distributed and enables predictable local drug release.

Permanently microstructured adhesive channels move moisture across the skin-contact layer to reduce float-off, irritation, and bacterial growth.

Antipathogenic agents keep curable bone filler and dental composite compositions sterile during storage without radiation-induced polymerization.

PEG-enabled cyanoacrylate adhesives dissolve povidone iodine and other antimicrobials without disrupting polymerization, improving wound infection prevention.

A triple-lipid adhesive barrier balances ostomy pouch adhesion with lower peristomal irritation by reducing water loss and supporting skin hydration.

An ethanol-water mediator lets ferric and aluminium chlorides work with PVA at pH 1-3, giving stable haemostasis and easier application.

A hydrophobic matrix and bioadhesive microparticles repel blood or mucus, then rapidly crosslink to tissue without UV or prolonged pressure.

Injectable embolic particles release basic agents in vivo to neutralize tumor lactic acidosis and improve TAE/TACE cell-killing efficacy.

An NaSS/MA or AA/HEMA aqueous grafting coating boosts covalent grafting and keeps cell-resistant surfaces stable through drying and sterilization.

A skin adhesive tuned for deformable body surfaces improves long-wear attachment and supports stable biosensor signal acquisition.