Moldable Bone Substitute Composition Without Injector Mixing
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Solution Overview
Problem
Conventional bone substitute compositions require mixing and injecting by an injector, which is inconvenient for physicians.
Innovation Solution
A bone substitute composition that transforms into a clayey form after mixing with a conditioning solution, allowing reshaping by hand, and hardens into a rigid skeletal substitute within 30 minutes, facilitating manual application.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Ease of operation
If conventional bone substitute compositions are used, then the bone substitute can be applied via injector, but the operation process is complex and inconvenient for physicians
Solution Approach 1:
The patent extracts the injection function from the bone substitute composition itself, allowing the composition to be applied manually without requiring an injector. This separates the application method from the material, simplifying the overall system and making it more convenient for physicians to use.
Solution Approach 2:
The bone substitute composition is designed to be self-applicable through manual handling. The material itself provides the necessary properties for easy manipulation and placement without requiring complex injection devices, making the system self-sufficient and easier to operate.
2Strength
If conventional bone substitute compositions are used, then the material can harden to form structural support, but the hardening process requires precise mixing and injection control
Solution Approach 1:
The patent modifies the chemical composition parameters of the bone substitute, incorporating specific ratios of calcium phosphate powder, polymer, and crosslinker that enable the material to achieve proper hardening and structural strength through simple mixing rather than precise injection control. The composition parameters are optimized to be tolerant of manual mixing variations.
3Productivity
If conventional bone substitute compositions are used, then the material can be delivered through injector, but the surgical procedure is time-consuming and inefficient
Solution Approach 1:
The patent segments the bone substitute into a pre-mixed composition that requires only simple combining with activating solution, eliminating the need for complex injection procedures. This segmentation of the application process into minimal steps significantly reduces surgical time and improves productivity.
Solution Approach 2:
The patent skips the intermediate injection step entirely, allowing the bone substitute to be applied directly through manual placement. This eliminates a time-consuming step in the traditional process, rushing through the application more efficiently while maintaining material performance.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Improves surgical convenience by enabling physicians to easily mold the composition to match bone defects without an injector, maintaining efficiency and reducing costs.
Implementation Method 1
the bone substitute composition may transform into a clayey bone substitute with plasticity after the bone substitute matrix is mixed with the conditioning solution
Implementation Method 2
the calcium ions of the CPC react with the phosphate ions in the conditioning solution and generate hydroxyapatite (Ca5(PO4)3) after the CPC is mixed with the conditioning solution
Implementation Method 3
the clayey bone substitute gradually hardens and transforms into a non-reshapable, rigid skeletal bone substitute
Data Source
AI summary
A bone substitute composition includes a bone substitute matrix and a conditioning solution. The bone substitute matrix includes 85% to 98% by weight of alkaline calcium phosphate powder, 1% to 10% by weight of a polymer, and 1% to 5% by weight of a crosslinker. The conditioning solution includes 90% to 97% by weight of water, 1% to 5% by weight of a phosphate, and 1% to 5% by weight of a water-soluble acidic compound.