Crosslinked Absorber Layer for Enzyme Sensor Sensitivity
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Solution Overview
Problem
Conventional enzyme sensors experience a decrease in detection sensitivity over time, especially when measurements are prolonged.
Innovation Solution
The enzyme sensor incorporates a layered structure with an absorber layer made from a polymeric material having a chemically bound crosslinked structure, which helps maintain detection sensitivity even during long-term measurements.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Duration of action of moving object
If conventional enzyme sensors are used for long-term measurements, then measurement duration is extended, but detection sensitivity decreases
Solution Approach 1:
The patent changes the chemical structure parameter of the absorber layer by introducing a crosslinked structure. This structural modification prevents the absorber layer from deteriorating over time, thereby maintaining detection sensitivity during long-term measurements while extending the usable measurement duration
Solution Approach 2:
The patent uses a composite absorber layer comprising a crosslinked structure formed by reacting a polyol with a isocyanate-containing compound. This composite material combines the absorption capability with the structural stability of the crosslinked network, preventing sensitivity degradation over time
2Ease of manufacture
If the absorber layer uses conventional materials, then manufacturing is simpler, but detection sensitivity deteriorates over time
Solution Approach 1:
The patent modifies the chemical composition parameter of the absorber layer by incorporating crosslinked structures through reactions between polyols and isocyanate-containing compounds. This change maintains ease of manufacture through straightforward chemical reactions while significantly improving the reliability and temporal stability of detection sensitivity
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
The use of a crosslinked absorber layer in the enzyme sensor effectively prevents a decline in detection sensitivity over time, ensuring consistent and reliable measurements.
Implementation Method 1
an absorber layer configured to absorb the secretion
Implementation Method 2
an enzyme layer containing an enzyme... detects, with the electrode part, electrode-detectable substances generated from the measurement target substance in the presence of the enzyme
Implementation Method 3
The absorber layer comprises a polymeric material having a chemically bound crosslinked structure
Data Source
AI summary
An enzyme sensor may be configured to measure a measurement target substance included in a secretion of a living body. The enzyme sensor may include a layered structure including, in this order, (a) an absorber layer configured to absorb the secretion, (b) an enzyme layer containing an enzyme, (c) a mediator layer, and (d) an electrode part. The absorber layer may include a polymeric material having a chemically bound crosslinked structure.