Dielectrophoresis Voltage Correction via Existing Electrode Impedance

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Solution Overview

Problem

Existing fluid chips require inspection electrodes and channels for voltage correction, leading to increased size and complexity.

Innovation Solution

A method and apparatus for correcting control voltage in a dielectrophoresis process that measures impedance between electrodes, calculates a correction coefficient using a mathematical formula, and adjusts the voltage based on this coefficient to ensure effective dielectrophoretic force application without the need for additional inspection electrodes or channels.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Manufacturing precision

If inspection electrodes and inspection channel are provided to execute voltage correction, then manufacturing precision is improved, but device complexity increases and size increases

Engineering Contradiction:
Improvevoltage correction precisionVSAvoidchip structure complexity
Core Design Contradiction:
Manufacturing precisionVSDevice complexity

Solution Approach 1:

The patent makes the main electrodes serve dual functions: both dielectrophoresis operation and impedance measurement for voltage correction. By measuring impedance between the main electrodes themselves rather than using separate inspection electrodes, the system achieves voltage correction capability without adding extra components, thus reducing device complexity while maintaining correction precision

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent combines the voltage correction function with the existing main electrodes by measuring impedance through them. This merging eliminates the need for separate inspection electrodes and inspection channels, integrating the correction mechanism into the existing structure and thereby reducing overall device complexity

Inventive Principle:
Principle #5Merging (Combining)

2Manufacturing precision

If inspection electrodes and inspection channel are provided to execute voltage correction, then manufacturing precision is improved, but the size of fluid chip increases

Engineering Contradiction:
Improvevoltage correction precisionVSAvoidfluid chip area
Core Design Contradiction:
Manufacturing precisionVSArea of stationary object

Solution Approach 1:

The main electrodes are made multi-functional by using them both for dielectrophoresis and for impedance measurement. This eliminates the need for separate inspection electrodes and channels that would occupy additional space, thereby maintaining voltage correction precision while reducing the overall chip area

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent merges the voltage correction measurement function into the existing main electrode structure. By using the same electrodes for both operation and measurement, the design eliminates redundant components and reduces the spatial requirements of the fluid chip

Inventive Principle:
Principle #5Merging (Combining)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This approach allows for precise control voltage correction, reducing the size of the fluid chip and minimizing parasitic component influence on separation and collection performance, while also reducing operational costs and environmental impact.

Implementation Method 1

measuring an impedance between the first electrodes in the fluid chip through the first fluid or a second fluid

Methodology Applied
Scientific EffectImpedance measurement: Electrical Resistance

Implementation Method 2

a control voltage that causes a dielectrophoretic force to act on dielectric particles contained in a first fluid injected into a fluid chip

Methodology Applied
Scientific EffectDielectrophoresis:

Data Source

PatentEP4631623A1Control voltage correction method and dielectrophoresis apparatus
Publication Date: 2025.10.15 SCREEN HOLDINGS CO LTD
  • EP4631623A1 patent drawingFigure 1
  • EP4631623A1 patent drawingFigure 2
  • EP4631623A1 patent drawingFigure 3

AI summary

The control voltage correction method corrects a control voltage (Vcn) that causes a dielectrophoretic force to act on dielectric particles (P1) contained in the first fluid injected into a fluid chip (11). The control voltage correction method includes a step (S2) of measuring an impedance (IM1) between first electrodes (43a, 43b) in a fluid chip (11) through the first fluid or a second fluid, a step (S3) of calculating a correction coefficient (C) based on the measured impedance (IM1) and a fluid impedance (IM2) derived by a mathematical formula, and a step (S4) of correcting a control voltage (Vcn) based on the correction coefficient (C). The fluid impedance (IM2) indicates an impedance of the first fluid or the second fluid. The first fluid is a fluid containing dielectric particles (P1) and other particles (P2). The second fluid is the same type of fluid as the fluid excluding the dielectric particles (P1) and the other particles (P2) from the first fluid.