External Neurostimulator with Percutaneous Electrodes for Cardiovascular Modulation
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Solution Overview
Problem
Current neurostimulation systems for modulating cardiovascular functions, particularly after acute myocardial infarction (MI), often require invasive implantation and are not suitable for temporary or intermittent use, making them unavailable or cost-ineffective when most needed.
Innovation Solution
A portable external neurostimulation system using transcutaneous and/or percutaneous electrodes, coupled with a bracing element, delivers neurostimulation through surface or percutaneous stimulation electrodes, allowing for immediate and temporary modulation of cardiovascular functions without the need for long-term implantation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If invasive implantable neurostimulation systems are used, then therapeutic effect is improved, but device complexity and invasiveness increase
Solution Approach 1:
The patent replaces invasive mechanical implantation with non-invasive transcutaneous electrical stimulation. The external neurostimulator delivers electrical signals through the skin to activate the vagus nerve, eliminating the need for surgical implantation while maintaining therapeutic efficacy for cardiovascular conditions.
Solution Approach 2:
The patent employs an external, removable neurostimulator that can be used temporarily or intermittently without permanent implantation. This approach reduces device complexity and cost compared to implantable systems, making it suitable for short-term post-MI therapy or patients who cannot undergo surgery.
2Duration of action of stationary object
If implantable neurostimulation systems are used, then long-term therapy is improved, but ease of operation and cost-effectiveness worsen
Solution Approach 1:
The patent creates a dynamic therapy system where the external neurostimulator can be easily applied, removed, or adjusted by the patient or caregiver. This flexibility allows the system to adapt to different treatment durations and patient needs, improving ease of operation compared to fixed implantable systems.
3Duration of action of stationary object
If implantable neurostimulation systems are used, then continuous therapy is improved, but ease of manufacture and cost-effectiveness worsen
Solution Approach 1:
The patent utilizes an external neurostimulator that can be manufactured more simply and at lower cost than implantable devices. The system is designed for temporary or intermittent use, eliminating the need for complex implantation procedures and specialized manufacturing processes required for permanent medical implants.
Applied Scientific Principles
This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.
Function Achieved in This Case
Provides a fast and cost-effective therapy response to cardiovascular disorders like acute MI, offering anti-remodeling and anti-arrhythmic effects without the invasive procedures associated with implantable systems.
Implementation Method 1
The external neurostimulator delivers neurostimulation percutaneously to a stimulation target in the body through the percutaneous stimulation electrode
Data Source
AI summary
A neurostimulation device includes an external neurostimulator worn by a patient using a bracing element that braces a portion of the patient's body. The external neurostimulator delivers neurostimulation to modulate a cardiovascular function of the patient. In one embodiment, the external stimulator delivers neurostimulation percutaneously to a stimulation target in the patient's body using at least one percutaneous stimulation electrode having a distal end lodged on or near the stimulation target.