Fish-Skin and Scale Collagen Peptide Extraction by Enzymatic Hydrolysis

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Solution Overview

Problem

Existing methods for extracting collagen peptides from fish skins and scales face challenges such as impurities, undesirable odors and tastes, and environmental hazards due to the use of chemicals, leading to increased production costs and complexity.

Innovation Solution

A non-chemical, environmentally friendly process involving pretreatment, enzymatic hydrolysis, and purification steps to produce high-quality collagen peptides from fish skins and scales, using controlled temperature and enzyme treatments to achieve specific molecular weights and peptide sequences.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If chemical methods are used to extract collagen peptides from fish skins and scales, then extraction efficiency is improved, but environmental harm and production cost increase

Engineering Contradiction:

Improveextraction efficiencyVSAvoidenvironmental harm

Core Design Contradiction:

ProductivityVSObject-affected harmful factors

Solution Approach 1:

The patent replaces chemical extraction methods with enzymatic hydrolysis using proteases. The enzyme collagenase specifically breaks down collagen proteins into peptides through biological catalysis, eliminating the need for harmful chemicals while maintaining extraction efficiency. This substitution of chemical systems with biological systems resolves the contradiction between extraction efficiency and environmental harm.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent optimizes process parameters including temperature (30-90°C), time (1-5 hours), and enzyme concentration to achieve efficient extraction without chemicals. By controlling these parameters, the enzymatic process achieves productivity comparable to chemical methods while avoiding environmental harm.

Inventive Principle:

Principle #35Parameter changes

2Productivity

If chemical methods are used to extract collagen peptides from fish skins and scales, then extraction efficiency is improved, but production cost increases

Engineering Contradiction:

Improveextraction efficiencyVSAvoidproduction cost

Core Design Contradiction:

ProductivityVSEase of manufacture

Solution Approach 1:

The patent replaces expensive chemical reagents and neutralization processes with cost-effective enzymatic hydrolysis. Proteases are used in controlled amounts, and the process eliminates the need for chemical neutralization and extensive purification steps, significantly reducing production costs while maintaining extraction efficiency.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent recovers and utilizes by-products from fish processing (skins and scales) that would otherwise be discarded. By converting these waste materials into valuable collagen peptides through enzymatic hydrolysis, the process reduces production costs and creates additional economic value.

Inventive Principle:

Principle #34Discarding and recovering

3Quantity of substance

If conventional extraction methods are used, then collagen peptides can be obtained, but impurities and undesirable odors remain

Engineering Contradiction:

Improvecollagen peptide yieldVSAvoidproduct purity

Core Design Contradiction:

Quantity of substanceVSManufacturing precision

Solution Approach 1:

The patent uses enzymatic hydrolysis to selectively break down collagen proteins into peptides, which naturally improves product purity. The enzyme action is specific and controlled, producing peptides with desired molecular weights and minimizing unwanted by-products and impurities that contaminate chemically extracted products.

Inventive Principle:

Principle #28Mechanics substitution (Replace mechanical system)

Solution Approach 2:

The patent optimizes extraction parameters including temperature, time, and pH to control the hydrolysis process and achieve high peptide purity. By controlling these parameters, the process produces collagen peptides with minimal impurities and undesirable odors, achieving both quantity and quality goals.

Inventive Principle:

Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The process results in collagen peptides with high protein content, minimal impurities, and specific peptide sequences, reducing production costs and environmental impact while maintaining quality.

Implementation Method 1

hydrolyzing the crude collagen by at least one protease enzyme

Methodology Applied

Scientific EffectEnzymatic hydrolysis: Enzyme

Implementation Method 2

The unique properties of collagen peptides make them suitable for utilization as ingredients and food supplements

Methodology Applied

Scientific EffectHydrolysis: Hydrolysis

Implementation Method 3

extracting a crude collagen from the pretreated fish skin using a heated water of 60 to 90° C. for 1 to 5 hours

Methodology Applied

Scientific EffectThermal extraction: Heating

Implementation Method 4

pretreating the fish skin with water at a temperature ranging from 30 to less than 60° C. for 10 to 30 minutes

Methodology Applied

Scientific EffectPretreatment:

Data Source

PatentUS20250212912A1Collagen peptide compositions from fish skins and scales and methods for producing same

Publication Date: 2025.07.03 THAI UNION GRP PUBLIC CO LTD

AI summary

Collagen peptide compositions and methods for producing these collagen peptide compositions from fish skin or fish scale are provided. The collagen peptide compositions are characterized by high protein content, minimal impurities, enriched hydroxyproline, and specific peptide sequences, making them suitable for use as supplements or additives in food and beverages.