Bacillus Velezensis Fish Scale Decomposition for Peptide Production

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Solution Overview

Problem

Existing methods for decomposing fish scales are limited, offering few alternatives for obtaining high-value products like peptides and amino acids, primarily focusing on collagen acquisition and using limited microorganisms.

Innovation Solution

Isolation and utilization of Bacillus velezensis strain CHB200, deposited as DSM 34894, which effectively decomposes fish scales to produce high-concentration peptides and amino acids, suitable for use in agricultural fertilizer, raw materials for skincare products, raw materials for skincare products, and medical materials, and medical products, etc. The strain CHB200 is used to produce materials containing peptides and amino acids.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Quantity of substance

If enzymatic hydrolysis subsequent to acid treatment is used to decompose fish scales, then collagen can be obtained, but the process is complex and collagen cannot be used directly by organisms

Engineering Contradiction:
Improvecollagen yieldVSAvoidprocess complexity
Core Design Contradiction:
Quantity of substanceVSDevice complexity

Solution Approach 1:

The patent extracts and utilizes specific enzymes (collagenase, protease, peptidase) from microorganisms to perform the decomposition function, separating the enzymatic activity from the complex multi-step chemical process. This allows direct extraction of usable peptides and amino acids from fish scales through biological decomposition, simplifying the overall process while maintaining high collagen yield.

Inventive Principle:
Principle #2Taking out (Extraction)

Solution Approach 2:

The patent introduces microorganisms as intermediary agents that naturally produce the necessary enzymes for decomposition. These microorganisms act as mediators between the fish scale substrate and the final peptide products, enabling a single-step biological decomposition process that replaces the complex acid treatment followed by enzymatic hydrolysis.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Adaptability or versatility

If limited microorganisms are used for fish scale decomposition, then few alternatives are available, but this restricts product diversity and optimization

Engineering Contradiction:
Improvemicroorganism selection rangeVSAvoiddecomposition efficiency
Core Design Contradiction:
Adaptability or versatilityVSProductivity

Solution Approach 1:

The patent identifies and utilizes multiple different microorganisms (Bacillus subtilis, Bacillus licheniformis, Bacillus amyloliquefaciens, Streptomyces albus) that can all perform fish scale decomposition. Each microorganism brings different enzymatic profiles and decomposition characteristics, providing universal solutions for various product requirements while maintaining high decomposition efficiency.

Inventive Principle:
Principle #6Universality (Multi-functionality)

Solution Approach 2:

The patent optimizes decomposition parameters including microorganism strain selection, incubation temperature, pH conditions, and substrate concentration to maximize decomposition efficiency. By adjusting these parameters, the system achieves high productivity with diverse microorganism options, resolving the contradiction between adaptability and productivity.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The strain CHB200 is capable of extracting specific applications in agricultural fertilizer, raw materials for skincare products, and medical products, and medical materials, and skincare products, and medical materials.

Implementation Method 1

a Bacillus velezensis capable of decomposing fish scales

Methodology Applied
Scientific EffectEnzymatic hydrolysis: Hydrolysis

Data Source

PatentUS20260002116A1Bacillus velezensis capable of decomposing fish scale
Publication Date: 2026.01.01 CH BIOTECH R&D
  • US20260002116A1 patent drawing
  • US20260002116A1 patent drawing
  • US20260002116A1 patent drawing

AI summary

A Bacillus velezensis capable of decomposing fish scales is provided and deposited in Leibniz Institute DSMZ-German Collection of Microorganisms and Cell Cultures with an accession number of DSM 34894.