FNZ142 Rumen Probiotic Feed Composition for Methane Reduction

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Solution Overview

Problem

Current methods for improving feed efficiency, growth, and reducing methane emissions in ruminant animals are inadequate, and there is a need for effective compositions and methods to inhibit methane-producing bacteria and archaea in the rumen microbiome to reduce greenhouse gas emissions.

Innovation Solution

The use of Lacticaseibacillus rhamnosus strain FNZ142, or its derivatives, in ruminant feed compositions to enhance feed efficiency, growth, and productivity, while inhibiting methane-producing bacteria and archaea, thereby reducing methane emissions and greenhouse gas footprints.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Productivity

If lactic acid bacteria are used as probiotics in ruminant animals, then feed efficiency and growth performance may be improved, but the effects are mixed and the mode of action is unclear

Engineering Contradiction:
Improvefeed efficiencyVSAvoidconsistency of effects
Core Design Contradiction:
ProductivityVSReliability

Solution Approach 1:

The patent identifies and utilizes specific functional parameters of Lacticaseibacillus rhamnosus FNZ142, including its ability to produce bacteriocins, modulate volatile fatty acid profiles, and inhibit methanogenesis. By focusing on these specific mechanistic parameters rather than general probiotic effects, the invention achieves consistent and reliable improvements in feed efficiency and growth performance.

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs Lacticaseibacillus rhamnosus FNZ142 as an intermediary microorganism that mediates between feed intake and productive output. The strain acts as a functional mediator by producing bacteriocins that inhibit harmful bacteria, modulating the rumen microbiome to reduce methane production, and improving nutrient utilization, thereby consistently enhancing feed efficiency and growth.

Inventive Principle:
Principle #24Intermediary (Mediator)

2Object-generated harmful factors

If lactic acid bacteria are used to reduce methane emissions from ruminants, then greenhouse gas emissions may be reduced, but the success has been limited

Engineering Contradiction:
Improvemethane emissionsVSAvoideffectiveness of methane reduction
Core Design Contradiction:
Object-generated harmful factorsVSReliability

Solution Approach 1:

The patent converts the harmful methane production process into a beneficial outcome by utilizing Lacticaseibacillus rhamnosus FNZ142 to inhibit methanogenic bacteria. The strain produces bacteriocins that specifically target and inhibit methanogens, thereby converting the harmful methane emission process into a reduced emission outcome, achieving reliable methane reduction.

Inventive Principle:
Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

The patent changes the functional parameters of the rumen microbiome by introducing Lacticaseibacillus rhamnosus FNZ142, which produces bacteriocins that inhibit methanogenesis. This parameter change in microbial community composition and function leads to consistent and reliable reduction in methane emissions, overcoming the limitations of previous probiotic approaches.

Inventive Principle:
Principle #35Parameter changes

3Productivity

If conventional feed compositions are used, then basic nutrition is provided, but feed efficiency and growth potential are not fully optimized

Engineering Contradiction:
Improvegrowth rateVSAvoidenergy conversion efficiency
Core Design Contradiction:
ProductivityVSLoss of energy

Solution Approach 1:

The patent introduces Lacticaseibacillus rhamnosus FNZ142 as a functional intermediary that mediates energy conversion efficiency in the rumen. The strain produces bacteriocins that inhibit harmful bacteria, modulates the microbiome to reduce methane production (which represents energy loss), and improves overall nutrient utilization, thereby optimizing both growth rate and energy conversion efficiency.

Inventive Principle:
Principle #24Intermediary (Mediator)

Solution Approach 2:

The patent replaces the passive mechanical digestion system with an active biological modulation system. By introducing Lacticaseibacillus rhamnosus FNZ142, the invention substitutes the purely mechanical feed conversion process with a biologically active system that produces bacteriocins, modulates microbiome composition, and enhances metabolic efficiency, leading to optimized growth and energy utilization.

Inventive Principle:
Principle #28Mechanics substitution (Replace mechanical system)

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The strain FNZ142 increases feed efficiency, enhances growth and productivity, improves body weight and milk production, and reduces methane emissions by altering the rumen microbiome, leading to improved energy utilization and lower greenhouse gas emissions.

Implementation Method 1

Lacticaseibacillus rhamnosus strain FNZ142... increasing feed efficiency, enhancing growth and/or productivity, improving body weight or body composition of a ruminant animal... The strain FNZ142 increases feed efficiency, enhances growth and productivity, improves body weight and milk production, and reduces methane emissions by altering the rumen microbiome

Methodology Applied
Scientific EffectFermentation: Fermentation

Implementation Method 2

inhibiting the growth of methane-producing bacteria and/or archaea in the forestomach of ruminant animals, reducing the ability of the rumen microbiome to produce methane

Methodology Applied
Scientific EffectCompetitive exclusion:

Implementation Method 3

inhibiting the growth of methane-producing bacteria and/or archaea... reducing methane emissions by a ruminant animal

Methodology Applied
Scientific EffectAntimicrobial action:

Data Source

PatentUS20250241339A1Use of lactic acid bacteria to improve feed efficiency
Publication Date: 2025.07.31 FONTERRA COOP GRP LTD
  • US20250241339A1 patent drawing

AI summary

This invention relates to use of a strain of probiotic bacteria or derivatives thereof for increasing feed efficiency, enhancing growth and/or productivity, improving body weight or body composition, and/or increasing milk production in a ruminant animal, inhibiting the growth of methane-producing bacteria and/or archaea in the forestomach of ruminant animals, reducing the ability of the rumen microbiome to produce methane, reducing methane emissions by a ruminant animal, and/or reducing the greenhouse gas emission footprint of a ruminant animal. Ruminant feed compositions are also provided.