Foldable Adhesive Dressing With Hinged Drug Reservoir

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Solution Overview

Problem

Current transdermal and topical drug delivery methods face limitations due to the barrier properties of the skin, and existing devices are often complex or limited in their ability to effectively deliver active ingredients, either by integrating multiple functions or requiring separate steps for skin treatment and drug delivery.

Innovation Solution

An adhesive composite dressing comprising an anchor member, a target member, and a folding member with a drug reservoir, where the folding member is attached to the anchor portion through a hinge, ensuring accurate alignment with treated skin areas, and can be used in conjunction with skin treatment devices like microneedle arrays or RF ablation devices.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of operation

If a single integrated device performs both skin treatment and drug delivery, then the administration process is simplified, but the device complexity increases and the amount of drug delivery is limited

Engineering Contradiction:
Improveadministration processVSAvoiddevice complexity
Core Design Contradiction:
Ease of operationVSDevice complexity

Solution Approach 1:

The system is divided into two separate components: a skin treatment device and a drug reservoir dressing. The skin treatment device is used first to create pores or increase permeability, then the drug reservoir dressing is applied separately to deliver the active ingredient. This segmentation allows each device to be optimized for its specific function while maintaining overall simplicity in the administration process.

Inventive Principle:
Principle #1Segmentation

2Ease of operation

If a single integrated device performs both skin treatment and drug delivery, then the administration process is simplified, but the amount of drug delivery is limited

Engineering Contradiction:
Improveadministration processVSAvoidamount of drug delivery
Core Design Contradiction:
Ease of operationVSQuantity of substance

Solution Approach 1:

By separating the skin treatment function from the drug delivery function, the system allows for optimized performance in each area. The drug reservoir can be designed with sufficient capacity to deliver the required amount of active ingredient without being constrained by the limitations of integrated device designs.

Inventive Principle:
Principle #1Segmentation

3Device complexity

If skin treatment and drug delivery are performed in separate steps, then the device design is simplified and flexibility is improved, but an additional user step is required

Engineering Contradiction:
Improvedevice designVSAvoiduser step
Core Design Contradiction:
Device complexityVSEase of operation

Solution Approach 1:

The skin treatment is performed as a preliminary action before drug delivery. The pores or increased permeability are created in advance using the skin treatment device, and then the drug reservoir dressing is applied to take advantage of the pre-prepared skin surface. This sequencing allows for simplified device design while maintaining ease of operation through a logical progression of steps.

Inventive Principle:
Principle #10Preliminary action

4Ease of operation

If the drug reservoir is placed on treated skin without alignment features, then the application is simpler, but the alignment precision with the treated area deteriorates

Engineering Contradiction:
ImproveapplicationVSAvoidalignment precision
Core Design Contradiction:
Ease of operationVSManufacturing precision

Solution Approach 1:

The dressing incorporates visual alignment features such as colored markers, patterns, or contrasting elements that correspond to the treated area. These visual cues enable the user to accurately position and align the drug reservoir with the treated skin area, ensuring precise delivery without complicating the application process.

Inventive Principle:
Principle #32Color changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The adhesive composite dressing ensures precise delivery of active ingredients to treated skin areas, enhancing drug permeability and flexibility in drug delivery, while simplifying the administration process and device design.

Implementation Method 1

the folding member is attached to the anchor portion through a hinge defined by a line of attachment that is not contiguous with an edge of the anchor member

Methodology Applied
Scientific EffectAdhesion: Adhesive

Data Source

PatentUS9849270B2Foldable adhesive composite dressing
Publication Date: 2017.12.26 KINDEVA DRUG DELIVERY LP
  • US9849270B2 patent drawing
  • US9849270B2 patent drawing
  • US9849270B2 patent drawing

AI summary

An adhesive composite dressing useful for applying an active ingredient to a treated skin site, as well as methods of manufacture and use of such dressings. In one embodiment, an adhesive composite dressing comprising an anchor member, a target member, and a folding member, where the anchor member comprises a first skin-contact adhesive, the target member comprises an opening adapted to enable skin treatment, the folding member comprises a drug reservoir, and where the folding member is attached to the anchor portion through a hinge defined by a line of attachment that is not contiguous with an edge of the anchor member.