Hybrid Corn CH350141 Breeding via CMS and Segmentation

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Solution Overview

Problem

Corn breeding techniques face challenges in developing uniform hybrid varieties with desirable traits such as high yield, disease resistance, and uniform germination due to genetic non-uniformity and unpredictability in cross-pollination, requiring the development of stable inbred plants and methods to prevent self-pollination.

Innovation Solution

The development of the hybrid corn variety CH350141, which includes genetic loci for traits like male sterility, herbicide resistance, and disease resistance, utilizing cytoplasmic-male sterility and transgenes integrated at specific chromosomal locations, and a method for controlled cross-pollination to produce uniform hybrid seeds.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Adaptability or versatility

If natural cross-pollination is used in corn breeding, then genetic diversity is improved, but genetic uniformity and predictability of hybrid performance deteriorate

Engineering Contradiction:

Improvegenetic diversityVSAvoidgenetic uniformity

Core Design Contradiction:

Adaptability or versatilityVSManufacturing precision

Solution Approach 1:

The breeding program segments the population into distinct inbred lines through repeated self-pollination, creating genetically uniform parental lines that when crossed produce uniform hybrids with predictable performance

Inventive Principle:

Principle #1Segmentation

Solution Approach 2:

Inbred parental lines are developed in advance through multiple generations of self-pollination and selection before the hybrid cross is made, ensuring genetic stability and uniformity in the final hybrid product

Inventive Principle:

Principle #10Preliminary action

2Manufacturing precision

If self-pollination is used to develop inbred lines, then genetic uniformity is improved, but ability to prevent self-pollination deteriorates

Engineering Contradiction:

Improvegenetic uniformityVSAvoidself-pollination prevention

Core Design Contradiction:

Manufacturing precisionVSObject-affected harmful factors

Solution Approach 1:

Cytoplasmic male sterility is used to convert the harmful effect of unwanted self-pollination into a beneficial tool for controlled hybrid seed production, ensuring that only cross-pollination occurs between designated parental lines

Inventive Principle:

Principle #22Blessing in disguise (Convert harm into benefit)

Solution Approach 2:

A cytoplasmic sterility factor acts as an intermediary mechanism to prevent self-pollination in the female parent, allowing controlled cross-pollination while maintaining genetic uniformity in hybrid production

Inventive Principle:

Principle #24Intermediary (Mediator)

Data Source

PatentUS7718866B2Plants and seeds of hybrid corn variety CH350141

Publication Date: 2010.05.18 MONSANTO TECHNOLOGY LLC

AI summary

According to the invention, there is provided seed and plants of the hybrid corn variety designated CH350141. The invention thus relates to the plants, seeds and tissue cultures of the variety CH350141, and to methods for producing a corn plant produced by crossing a corn plant of variety CH350141 with itself or with another corn plant, such as a plant of another variety. The invention further relates to genetic complements of plants of variety CH350141.