Hydroxypyrion and Silver Biocidal Compositions
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Solution Overview
Problem
Current biocides are inadequate in providing comprehensive protection against a broad range of microorganisms, including bacteria, fungi, yeasts, and viruses, which can cause deterioration of materials and pose health risks, especially in environments like wood, textiles, and agricultural products.
Innovation Solution
A combination of hydroxypyrion compounds (such as 1-hydroxy-2-pyridinone, ciclopirox, and their derivatives) with silver compounds (like silver acetate and nano-silver particles) is used to create a synergistic biocidal effect, offering protection against microorganisms by inhibiting their growth and proliferation.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If current biocides are used to protect materials against microorganisms, then some level of protection is provided, but the protection is inadequate against a broad range of microorganisms including bacteria, fungi, yeasts, and viruses
Solution Approach 1:
The patent combines hydroxypyrone compounds (which are effective against fungi and yeasts) with silver compounds (which are effective against bacteria and viruses) to create a synergistic biocidal composition. This merging of two different biocidal mechanisms provides comprehensive broad-spectrum protection against all four major types of microorganisms while maintaining high reliability through the synergistic enhancement of their combined effectiveness.
2Adaptability or versatility
If higher concentrations of single biocides are used to achieve broad-spectrum protection, then coverage improves, but the risk of resistance development and environmental harm increases
Solution Approach 1:
The patent changes the parameter of biocidal composition from single-substance high concentration to multi-substance low concentration. By combining hydroxypyrone and silver compounds in synergistic ratios, the patent achieves broad-spectrum coverage at lower individual concentrations, thereby reducing the selective pressure that drives resistance development and minimizing environmental harm while maintaining effective broad-spectrum protection.
3Reliability
If combination of hydroxypyrone compounds and silver compounds is used, then synergistic biocidal effect is achieved, but the complexity of composition formulation increases
Solution Approach 1:
The patent creates a composite biocidal material combining hydroxypyrone compounds and silver compounds in specific synergistic ratios. This composite formulation integrates two different biocidal mechanisms into a single coordinated system, achieving enhanced reliability through synergistic effects while managing formulation complexity through defined compositional parameters and standardized preparation methods.
Data Source
AI summary
The present invention relates to combinations of hydroxypyrion compounds, and silver compound which provide an improved biocidal effect. More particularly, the present invention relates to compositions comprising a combination of a hydroxypyrion compound selected from 1 -hydroxy-2-pyridinone, ciclopirox, ciclopirox olamine, piroctone, piroctone olamine, rilopirox, or a salt thereof, together with one or more silver salts selected from silver acetate, silver alginate, silver azide, silver citrate, silver lactate, silver nitrate, silver perchlorate, silver sulfate, silver chloride, silver thiocyanate, silver-sodium-hydrogen-zirconium phosphate, silver sulfadiazine, silver cyclohexanediacetic acid and disilver 2,5-dichloro-3,6-dihydroxy-2,5-cyclohexadiene- 1,4-dione in respective proportions to provide a synergistic biocidal effect. Compositions comprising these combinations are useful for the protection of any living or non-living material, such as crops, plants, fruits, seeds, objects made of wood, thatch or the like, engineering material, biodegradable material and textiles against deterioration due to the action of microorganisms such as bacteria, fungi, yeasts, algae, virusses, and the like.