Biocide TRIZ Cases

A dried microbial supernatant and surfactant powder controls plant disease, boosts water uptake, and helps keep irrigation flow efficient.

Combining substituted pyridines with fungicides of different modes of action broadens fungal control and slows resistance development in crops.

Chimeric Bacillus-derived polypeptides expand crop resistance beyond narrow pest targets, reducing chemical insecticide use.

Structured disulfide compounds target microbial propagation in resistant infections while balancing antimicrobial activity with host-cell safety.

Elasnin-based compositions target resistant biofilms, inhibiting formation and disrupting mature growth with less reliance on high-dose antibiotics.

Selected Methylobacterium isolates applied from V6 to R3 improve corn early vigor and increase yield by 2–20%, addressing weak conventional strains.

A halogenated poly(melamine-silicate)-metal oxide composite improves pathogen neutralization while addressing resistance, safety, and reuse.

A PCAT transporter and membrane fusion protein let gram-negative bacteria export heterologous peptides while preserving peptide integrity and activity.

Shell fragments with chitin and dispersed biocidal metal enable steady anti-fouling release over time while reducing environmental harm.

Slow hydrolysis releases menthol over time, extending cooling while supporting solubility and flavor in oral care, edible, and repellent products.

A five-membered heteroaryl fungicide maintains strong pathogen control while reducing plant, soil, livestock, and fish toxicity through ring-structure changes.

Sequence-modified antimicrobial polypeptides retain broad-spectrum activity while improving neutral/alkaline pH stability and heat tolerance.

Applying ethoxylated oil bioactive solutions helps plants maintain growth and drought tolerance while reducing water requirements.

Polar and semi-polar solvent formulations keep plant growth regulators stable without water-driven degradation while preserving crop activity.

Conventional sea lice treatments lose efficacy as resistance develops; cyclopropylamide compounds provide prolonged control with low fish toxicity.

Enhanced dissolution lets pharmaceutical-grade ferric citrate bind gastrointestinal phosphate at lower doses, helping limit adverse effects in chronic kidney disease.

A defined hydrazide structure targets agricultural and horticultural pathogens, combining stable bactericidal activity with industrially feasible synthesis.

Selective 5-HT2A activity from fused gamma-carbolines targets psychosis and sleep disorders while limiting extrapyramidal side effects.

Combines a herbicidal compound with insecticidal, nematicidal, and fungicidal treatments across seeds and foliage for broader crop protection.

Systematic substituent changes create alkoxypyridine and alkoxypyrimidine derivatives for effective control of fungal plant diseases.

Nitrogen-containing heterocycles coordinate silver with selected metals, limiting UV- and chloride-driven coloration while preserving biocidal activity.

Substituted oxadiazolone groups control barnyard grass, crabgrass, and abutilon while maintaining safety for corn and rice.

Flooding limits soybean oxygen supply and metabolism; KHP treatment supports root development, nutrient uptake, and growth under stress.

Herbicide-tolerant biocontrol agents survive treated soils, compete with microbes, suppress pathogens, and support plant growth.

FOS and yeast cell extract feed target bacteria and fungi on plants, extending survival and reducing repeated biopesticide applications.

PERK13 inhibition reduces sodium ion influx, helping plants tolerate sodium chloride concentrations of 1.0% by mass or more.

A defined phage composition targets Xylella fastidiosa, inhibiting bacterial growth as an environmentally friendly way to control plant disease.

A lytic phage with a short non-contractile tail infects Xylella fastidiosa, reducing plant disease symptoms without chemical pesticides.

Conventional culture quickly loses antibody-secreting cells; MSC-derived signals, saccharide, APRIL, and buffering support survival beyond 56 days.

Boron compounds stabilize cerium oxide nanoparticles while increasing oxidative degradation for antiviral and antibacterial dispersions.

A water infusion of horsetail, rose hips, and soapwort supports plant growth and resistance to abiotic stress.

Cold plasma activates horsetail, rosehip, and soapwort extracts into a plant biostimulator for growth and stress resistance.

Microwave activation of horsetail, rose hips, and soapwort produces a water-based biostimulator for plant growth and stress resistance.

Chrysanthemum-derived insecticides in biodegradable housing kill ticks without synthetic pesticides, reducing environmental harm.

Variant Cry1B polypeptides broaden Bt-based pest protection in transgenic crops across Lepidopteran and Coleopteran pests.

A flexible, non-contractile-tail bacteriophage targets Xylella fastidiosa for plant disease control without chemical treatments.

Specific heteroaryl azole structures address resistant insects and mites at lower concentrations while limiting phytotoxicity and non-target toxicity.

Specific Methylobacterium isolates are disclosed for improving soybean yield by 2–20% over untreated controls through targeted plant applications.

Combining triclopyr with phosphate ester adjuvants speeds observable phytotoxicity and improves residual control of plant growth.

Peracid sanitation reduces contaminating bacteria in ethanol fermentation while preserving yeast growth and avoiding antibiotic residues in animal feed.

Combining distinct herbicide modes of action helps address weed resistance while extending control and reducing crop damage.

Multiple quaternary ammonium groups and tuned hydrophobic tails address bacterial resistance while supporting lower-toxicity antimicrobial use.

Biocide particles at least 20 μm in volume mean diameter improve retention through hot pressing and block stacking, reducing required application amounts.

Metal oxide capsule shells combine dense low-permeability protection with controlled payload release under friction.

Wild Glycine tomentella resistance genes are introduced into commercial soybeans to strengthen Asian Soybean Rust resistance and reduce yield losses.

Novel substituted bicyclic compounds address resistance concerns while targeting insects, arachnids, and nematodes with broad pesticidal activity.

Inducible uAT expression deactivates glutamine synthetase for controlled ammonia release, helping limit metabolic burden and support diazotroph longevity.

Combining sulfosuccinate and additional surfactants improves pesticide absorption, temperature stability, viscosity, and plant-surface spreading.

Defined aryl, heteroaryl, alkyl, and haloalkyl substituents improve pyridone herbicidal activity while limiting impact on useful crops.

A nitrogen-containing oxime compound targets weeds while maintaining high crop safety for more effective herbicide development.

Divided poly-ICLC dosing intervals maintain immune activation while avoiding high-dose toxicity.

Amorphous calcium phosphate nanoparticles release ions to neutralize acids and inhibit bacterial growth, preventing secondary caries in dental restorations.

A grease-like gel composition uses capsaicin to create a burning sensation on rodent feet for effective deterrence.

Modified phenylpyrazole structure overcomes pest resistance while maintaining crop safety through targeted substituent placement.

Spray drying gram-negative bacteria using protective carriers like lactose maintains biological activity despite thermal stress.

Amino esters assemble into nanoparticles to kill microorganisms, replacing heavy metals and unstable peptides with biodegradable compounds.

Removing the A-ring exocyclic methylene group from 19-nor-vitamin D analogs reduces calcemic activity while maintaining therapeutic efficacy.

Triazole spacer arms in solanidine compounds overcome pest resistance by increasing molecular flexibility and enzymatic inhibition.

Aeration triggers extracellular enzyme release in biopesticides, resolving low efficacy and chemical toxicity trade-offs.

Atomic layer deposition coats porous polymer scaffolds with nanometer-thick ceramic films to enhance cell adhesion.

Acylguanidine derivatives modulate the 5-HT5A receptor via a carbonyl-linked bicyclic structure to treat dementia and schizophrenia.

Periodic magnetic fields drive microsphere deformation, balancing high drug release rates with precise timing control.

Male-specific pheromone targets female Tribolium castaneum, resolving the trade-off between broad attraction and controlled bioinsecticide activation.

Bicyclic spiro compounds selectively modulate the M1 muscarinic receptor to activate PKC and inhibit GSK-3β.

New amide structures overcome emerging fungal resistance while maintaining synthesis feasibility through parameter changes and composite materials.

Applying kinetin with low-potassium concentrations during flowering blocks heat-induced autophagy to maintain seed development.

Topical alkanolamide formulations inhibit Langerhans cell migration, addressing the bottleneck of uncontrolled immune responses in inflammatory dermatoses.

In situ generation extends residence time, reducing volatility and plant damage.

Self-assembling peptide nanofiber scaffolds resolve scaffold stability and immune rejection contradictions by enabling targeted cell placement.

High-boiling terpene solvents prevent rapid evaporation during thermal fogging, ensuring uniform CIPC deposition without crystal formation.

A 293SF packaging cell line grows in suspension to produce high-titer non-replicative retroviruses.

Combining hydroxypyrion compounds with silver salts creates a synergistic biocidal composition.

Imino compounds featuring a 2-chloropyrimidin-5-yl substituent address insufficient pesticidal activity against difficult-to-control insects and acarid pests.

A folate-targeted liposomal mitomycin C prodrug composition increases intracellular drug concentration in bladder cancer cells.

Nicotinamide riboside and nicotinamide mononucleotide derivatives increase intracellular NAD+ concentrations in mammalian cells.

Indole-1-acetic acid derivatives featuring a 2-benzenesulfonyl-pyridin-3-yl group act as potent CRTH2 antagonists.

Valerenic acid derivatives modify molecular structure to increase affinity for GABAA receptors, reducing addiction risks associated with benzodiazepines.

A smooth coating layer prevents pests from scaling vertical structures, resolving the trade-off between bulky physical barriers and effective exclusion.

Segmented pro-drugs with electron-withdrawing substituents lower nucleophile basicity, preventing excessive plasma levels through enzymatic cleavage.

A water-solubilizing preparation combines polyglycerin fatty acid esters with specific surfactants to form stable microemulsions.

Beneficial microorganisms boost crop productivity and stress tolerance without genetic modification or chemical fertilizers.

Modified prostaglandin analogs lower intraocular pressure while improving metabolic stability against degradation.

Adding Rhizobium bacteria to soil alters the microbial community and boosts plant antioxidant activity.

Macrocyclic picolinamides control ascomycetes, basidiomycetes, deuteromycetes, and oomycetes while reducing application complexity.

Isolating somatic stem cells via density separation and differentiating them into dendritic cells for tissue repair.

A secondary calcium and magnesium phosphonate mixture controls phytopathogenic fungi while acting as a plant nutrient.

Benzothiazol-one derivatives bind to allosteric sites on mGluR2 receptors, resolving specificity trade-offs in glutamate modulation.

A polyglycerol fatty acid ester and nonionic surfactant composition inhibits pest movement and blocks spiracles.

Glycerin and oil barrier layer slows nitrogen nitrification in soil while providing broad-spectrum pest control.

A synergistic microbicidal composition combines a nonionic surfactant with benzoate or sorbate salts to inhibit microbial growth in aqueous media.

Segmenting protein kinases into specific families and modifying chemical parameters yields targeted inhibitors that treat cancers.

Dinitroaniline compounds control resistant weeds while preventing resistance development in populations.

Stabilized peroxide coatings kill pathogens rapidly without leaving toxic residues, solving resistance issues from conventional agents.

Fused pyridine derivatives inhibit DPP-IV to protect GLP-1, addressing the long-term efficacy loss of current anti-diabetic drugs.

Novel imidazopyridazine compounds overcome resistance in agricultural pests while maintaining broad-spectrum efficacy across multiple insect orders.