Peracid Sanitation of Ethanol Fermentation for Bacterial Control

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Solution Overview

Problem

The biofuel industry faces challenges in ethanol fermentation due to bacterial contamination, which reduces production yields and efficiency, and the use of antibiotics in fermentation processes leads to undesirable incidental dosing in animal feed and regulatory concerns.

Innovation Solution

Employing peracid compositions, particularly peroxyoctanoic acid, to sanitize fermentation systems and eliminate microbial populations without interfering with yeast fermentation, thereby improving ethanol yield and avoiding residual animal feed concerns.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Reliability

If antibiotics are used to control yield loss bacterium in fermentation, then bacterial contamination is reduced, but antibiotic residues are incidentally dosed into animal feed supplies

Engineering Contradiction:
Improvecontrol of yield loss bacteriumVSAvoidantibiotic residues in animal feed
Core Design Contradiction:
ReliabilityVSObject-generated harmful factors

Solution Approach 1:

The patent changes the chemical parameter of the antimicrobial agent from antibiotics to peracid compositions (such as peracetic acid, peroxypropionic acid, or blends with organic acids). This parameter change eliminates antibiotic residues in animal feed while maintaining effectiveness against yield loss bacteria like Lactobacillus and Acetobacter species during corn ethanol fermentation

Inventive Principle:
Principle #35Parameter changes

Solution Approach 2:

The patent employs peracid compositions that decompose into harmless byproducts (water, oxygen, and carbon dioxide) rather than persisting as residues. These short-living antimicrobial agents provide effective bacterial control during fermentation without creating long-term contamination issues in the food supply chain

Inventive Principle:
Principle #27Cheap short-living objects (Disposable)

2Reliability

If peracid compositions are used to sanitize fermentation systems, then microbial populations are reduced, but the system requires effective sanitation without interfering with yeast fermentation

Engineering Contradiction:
Improvereduction of microbial populationsVSAvoidcompatibility with yeast fermentation
Core Design Contradiction:
ReliabilityVSAdaptability or versatility

Solution Approach 1:

The patent applies peracid compositions at specific locations and concentrations tailored to different fermentation system components. The sanitation approach varies by location (fermenter surfaces, pipes, equipment) and adjusts the peracid concentration to achieve microbial reduction while maintaining yeast viability and fermentation performance

Inventive Principle:
Principle #3Local quality

Solution Approach 2:

The patent implements periodic sanitation cycles using peracid compositions during the fermentation process. This includes applying peracids at specific stages (such as before substrate loading or during maintenance periods) to control bacterial populations without continuously exposing the yeast to antimicrobial agents that could inhibit fermentation

Inventive Principle:
Principle #19Periodic action

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

The use of peracid compositions effectively reduces microbial populations, enhancing ethanol yield and ensuring compliance with regulatory standards by eliminating antibiotic residues in animal feed.

Implementation Method 1

The use of peracid compositions, particularly peroxyoctanoic acid, to sanitize fermentation systems and eliminate microbial populations

Methodology Applied
Scientific EffectOxidation: Oxidation

Data Source

PatentUS12460232B2Methods for reducing and/or eliminating microbial populations in a fermentation process
Publication Date: 2025.11.04 ECOLAB USA INC
  • US12460232B2 patent drawing
  • US12460232B2 patent drawing
  • US12460232B2 patent drawing

AI summary

A process for the use of peracid compositions to eliminate and/or control the growth of undesirable bacteria, including contaminating bacteria, in the fermentation production of alcohol is disclosed. Beneficially, the peracid compositions and methods of use of the same do not interfere or inhibit the growth or replication of yeast and have low or no adverse environmental impact.