Demountable ICP Torch Holder With External Plasma Ignition

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Solution Overview

Problem

Current inductively coupled plasma (ICP) analysis systems face challenges in maintaining efficient plasma generation and sample analysis, particularly in mass cytometry, due to limitations in torch design and ignition methods, which complicate maintenance and reduce operational efficiency.

Innovation Solution

The development of a demountable ICP torch holder assembly with an external ignition device using dielectric barrier discharge and an ICP load coil with an annular fin, allowing for easier maintenance and improved plasma stability, along with advanced sample introduction fluidics for efficient sample processing.

Engineering Contradictions & Design Principles

VSEngineering Contradiction Analysis

1Ease of repair

If a traditional integrated ICP torch design is used, then plasma generation is maintained, but maintenance complexity increases and operational efficiency decreases

Engineering Contradiction:
Improvemaintenance easeVSAvoidtorch design complexity
Core Design Contradiction:
Ease of repairVSDevice complexity

Solution Approach 1:

The ICP torch is divided into separate modular components including the torch body, torch holder, and load coil assembly that can be independently removed and maintained. The torch holder serves as a demountable interface that retains the torch body while allowing easy access for maintenance operations without affecting other system components.

Inventive Principle:
Principle #1Segmentation

2Reliability

If conventional ignition methods are used, then plasma ignition is achieved, but ignition reliability is insufficient and operational stability is reduced

Engineering Contradiction:
Improveignition reliabilityVSAvoidignition system complexity
Core Design Contradiction:
ReliabilityVSDevice complexity

Solution Approach 1:

An external ignition device is introduced as an intermediary component that generates a spark discharge to reliably ignite the plasma in the ICP torch. The ignition device includes electrodes positioned to create a discharge across the torch inlet, providing consistent and reliable plasma ignition without requiring modifications to the torch structure itself.

Inventive Principle:
Principle #24Intermediary (Mediator)

3Reliability

If high outer gas flow is used, then plasma stability is maintained, but gas consumption increases and operational cost rises

Engineering Contradiction:
Improveplasma stabilityVSAvoidgas consumption
Core Design Contradiction:
ReliabilityVSLoss of substance

Solution Approach 1:

The system optimizes plasma stability by adjusting operational parameters including reduced outer gas flow rates combined with optimized RF power levels and improved torch alignment. The modular torch holder design allows for precise positioning of the torch body to maximize plasma confinement and stability while minimizing gas consumption through optimized flow paths and reduced turbulence.

Inventive Principle:
Principle #35Parameter changes

Applied Scientific Principles

This section explains which scientific principles are used to turn an abstract innovation direction into a practical engineering solution.

Function Achieved in This Case

This configuration enhances the longevity and ease of maintenance of ICP components, reduces the need for outer gas flow, and enables reliable plasma ignition, thereby improving the efficiency and productivity of ICP analysis systems, particularly in mass cytometry applications.

Implementation Method 1

an external ignition device using dielectric barrier discharge

Methodology Applied
Scientific EffectDielectric barrier discharge: Dielectric Heating

Implementation Method 2

ICP load coil with an annular fin

Methodology Applied
Scientific EffectElectromagnetic induction: Electromagnetic Induction

Implementation Method 3

ICP analyzers use an ICP torch to generate a plasma in which a sample is atomized an ionized

Methodology Applied
Scientific EffectPlasma: Plasma

Data Source

PatentUS12087568B2Inductively coupled plasma based atomic analysis systems and methods
Publication Date: 2024.09.10 STANDARD BIOTOOLS CANADA INC
  • US12087568B2 patent drawing
  • US12087568B2 patent drawing
  • US12087568B2 patent drawing

AI summary

Inductively coupled plasma (ICP) analyzers use an ICP torch to generate a plasma in which a sample is atomized an ionized. Analysis of the atomic ions can be performed by atomic analysis, such as mass spectrometry (MS) or atomic emission spectrometry (AES). Particle based ICP analysis includes analysis of particles such as cells, beads, or laser ablation plumes, by atomizing and ionizing particles in an ICP torch followed by atomic analysis. In mass cytometry, mass tags of particles are analyzed by mass spectrometry, such as by ICP-MS. Systems and methods of the subject application include one or more of: a demountable ICP torch holder assembly, an external ignition device; an ICP load coil comprising an annular fin, particle suspension sample introduction fluidics, and ICP analyzers thereof.