Light Characteristic Determination for Ocular Cell Control
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Solution Overview
Problem
Secondary cataracts, caused by the proliferation of lens epithelial cells after cataract surgery, lead to clouding of the posterior capsule and decreased visual function, necessitating frequent surgical interventions.
Innovation Solution
A method to determine the characteristics of light that cause morphological changes and migration alterations in ocular cells, involving the acquisition and selection of relationships between light wavelength, irradiance, and cellular responses, to identify optimal light conditions for preventing secondary cataracts.
Engineering Contradictions & Design Principles
Engineering Contradiction Analysis
1Reliability
If cataract surgery is performed to remove the crystalline lens, then visual function is improved, but secondary cataract occurs due to lens epithelial cell proliferation
Solution Approach 1:
The patent applies preliminary anti-action by determining safe light characteristics (wavelength and irradiance) before cataract surgery to prevent lens epithelial cell proliferation. The method identifies light conditions that do not cause morphological changes or migration in lens epithelial cells, and recommends avoiding these light conditions in the post-operative period to prevent secondary cataract formation.
Solution Approach 2:
The patent applies preliminary action by acquiring relationships between light characteristics and lens epithelial cell responses in advance. The system determines safe light parameters before surgery and provides guidance for post-operative light exposure, enabling preventive measures to be taken before secondary cataract develops.
2Reliability
If YAG laser is used to remove turbidity in secondary cataract, then visual function is restored, but additional surgical intervention is required
Solution Approach 1:
The patent applies preliminary action by determining safe light characteristics before cataract surgery to prevent lens epithelial cell proliferation. The method identifies light conditions that do not cause morphological changes or migration in lens epithelial cells, and recommends avoiding these light conditions in the post-operative period to prevent secondary cataract formation.
Solution Approach 2:
The patent converts the harmful effect of light on lens epithelial cells into a beneficial preventive measure. By identifying specific light characteristics that trigger cell proliferation and migration, the system enables patients to avoid these light conditions post-operatively, thereby preventing secondary cataract and eliminating the need for YAG laser intervention.
3Object-affected harmful factors
If light with certain wavelength and irradiance enters the eye, then lens epithelial cell morphology changes and migration occurs, but this information can be used to prevent secondary cataract
Solution Approach 1:
The patent applies feedback by using the determined relationships between light characteristics and lens epithelial cell responses to provide post-operative light exposure guidance. The system feeds back safe light parameters to patients, enabling them to adjust their light exposure habits to prevent secondary cataract formation.
Solution Approach 2:
The patent applies parameter changes by identifying specific wavelength and irradiance thresholds that trigger lens epithelial cell proliferation and migration. The system uses these parameter thresholds to define safe light exposure conditions and provides guidance to patients on maintaining light parameters within safe ranges post-operatively.
Data Source
AI summary
A method of determining characteristics of light, including: a relationship acquisition step of, with respect to a subject, obtaining in advance a relationship 1 between a wavelength and irradiance of light that decides whether or not a morphological change of an ocular cell is caused and a relationship 2 between the wavelength and irradiance of the light that decides whether or not migration of the ocular cell is changed; a relationship selection step of selecting at least any of the relationship 1 and the relationship 2 depending on a degree 1 that is required for the morphological change and a degree 2 that is required for the cell migration; and a determination step of determining a wavelength and irradiance of light to be incident on the subject's eye based on the selected relationship.